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Cytokeratin 18 Antibody (B-6) is a mouse monoclonal IgG1 antibody that detects Cytokeratin 18 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Cytokeratin 18 is a vital component of the cytoskeleton in epithelial cells, contributing significantly to structural integrity and resilience. Cytokeratin 18 is predominantly located in the cytoplasm, forming a network of intermediate filaments that provide mechanical support and shape to cells. Proper localization of Cytokeratin 18 is crucial for maintaining epithelial tissue architecture, and disruption can lead to various pathological conditions, including cancer. Cytokeratin 18 serves as a biomarker for epithelial-derived tumors, as expression levels can indicate differentiation status of malignant cells. Post-translational modifications of Cytokeratin 18, such as phosphorylation, can influence protein interactions and overall cellular function. Anti-Cytokeratin 18 antibody (B-6) serves as an essential tool for researchers studying epithelial biology and cancer pathology, providing insights into Cytokeratin 18′s role in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 18 Antibody (B-6) | sc-398871 | 200 µg/ml | $322.00 | |||
Cytokeratin 18 Antibody (B-6): m-IgG Fc BP-HRP Bundle | sc-540951 | 200 µg Ab; 10 µg BP | $361.00 | |||
Cytokeratin 18 Antibody (B-6): m-IgG1 BP-HRP Bundle | sc-542484 | 200 µg Ab; 20 µg BP | $361.00 |