cyclin B3 Antibody (G-4): sc-515917

Cyclin B3 Antibody (G-4) is a mouse monoclonal IgG3 antibody that detects cyclin B3 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cyclin B3, also known as CCNB3 or CYCB3, is a 1,395 amino acid nuclear protein that plays a crucial role in the regulation of the meiotic cell cycle, particularly during early meiotic prophase I. Anti-cyclin B3 antibody (G-4) targets a protein predominantly expressed in the testis, with lower levels found in various other tissues, highlighting its specialized function in gametogenesis. Cyclin B3 forms complexes with cyclin-dependent kinases, which are essential for the proper progression of meiosis. Notably, cyclin B3 undergoes alternative splicing, resulting in three distinct isoforms, which may have unique regulatory roles or interactions within the cell. The dynamic expression and stability of cyclin B3 during the cell cycle are critical for ensuring that meiotic events occur at the appropriate times, thereby maintaining genomic integrity and fertility. Cyclin B3 monoclonal antibody (G-4) is an invaluable tool for researchers studying cell cycle regulation and reproductive biology, providing insights into the mechanisms underlying meiosis and potential implications for fertility-related disorders.

The preferred cyclin B3 antibody is cyclin B3 Antibody (E-8): sc-515887.