cyclin A1 Antibody (XLA1-1): sc-53233
- cyclin A1 Antibody (XLA1-1) is a mouse monoclonal IgG1, cited in 2 publications, provided at 200 µg/ml
- raised against Xenopus cyclin A
- recommended for detection of Xenopuscyclin A1 of x origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for cyclin A1 Antibody (XLA1-1). This work is in progress.
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Cyclin A1 Antibody (XLA1-1) is a mouse monoclonal IgG1 antibody that detects cyclin A1 in species reactivity X by western blotting (WB). Anti-cyclin A1 antibody (XLA1-1) plays a pivotal role in studying the regulation of the cell cycle, particularly in germ cells, where cyclin A1 is most highly expressed. Cyclin A1 is crucial for proper progression of meiosis, helping to control the transition from G1 phase to S phase, ensuring accurate DNA replication. Cyclin A1′s importance extends beyond cell cycle regulation, showing interactions with various cyclin-dependent kinases, including Cdk2 and Cdc2 p34, which are essential for activating key processes in cell division. Additionally, cyclin A1′s high sequence homology to Xenopus cyclin A1 suggests evolutionary conservation of function, highlighting significance in reproductive biology. Cyclin A1 (XLA1-1) monoclonal antibody serves as an invaluable tool for researchers studying cell cycle dynamics and molecular mechanisms underlying germ cell development.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
cyclin A1 Antibody (XLA1-1) References:
- Cyclin A1 expression and paclitaxel resistance in human ovarian cancer cells. | Huang, KC., et al. 2016. Eur J Cancer. 67: 152-163. PMID: 27669502
- Cyclin A1 is associated with poor prognosis in oesophageal squamous cell carcinoma. | He, X., et al. 2019. Oncol Lett. 18: 706-712. PMID: 31289545
- Overexpression of cyclin A1 promotes meiotic resumption but induces premature chromosome separation in mouse oocyte. | Li, J., et al. 2020. J Cell Physiol. 235: 7136-7145. PMID: 32030765
- Cyclin A1 in Oocytes Prevents Chromosome Segregation And Anaphase Entry. | Radonova, L., et al. 2020. Sci Rep. 10: 7455. PMID: 32366979
- Deubiquitinating enzyme inhibitor alleviates cyclin A1-mediated proteasome inhibitor tolerance in mixed-lineage leukemia. | Ge, M., et al. 2021. Cancer Sci. 112: 2287-2298. PMID: 33738896
- 1,6-Hexanediol regulates angiogenesis via suppression of cyclin A1-mediated endothelial function. | Jiang, Y., et al. 2023. BMC Biol. 21: 75. PMID: 37024934
- PICH Activates Cyclin A1 Transcription to Drive S-Phase Progression and Chemoresistance in Gastric Cancer. | Ye, H., et al. 2023. Cancer Res. 83: 3767-3782. PMID: 37646571
- [Cyclin A1 affects the invasion, metastasis, and prognosis of hepatocellular carcinoma]. | Ma, YR., et al. 2023. Zhonghua Gan Zang Bing Za Zhi. 31: 1043-1050. PMID: 38016768
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cyclin A1 Antibody (XLA1-1) | sc-53233 | 200 µg/ml | $322.00 |