CTF18 Antibody (B-7): sc-376074
- CTF18 Antibody (B-7) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 887-975 mapping at the C-terminus of CTF18 of human origin
- recommended for detection of CTF18 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CTF18 Antibody (B-7) for WB applications. These reagents are now offered in bundles with CTF18 Antibody (B-7) (see ordering information below).
QUICK LINKS
SEE ALSO...
CTF18 Antibody (B-7) is a mouse monoclonal IgG1 antibody that detects CTF18 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CTF18, or chromosome transmission fidelity factor 18 homolog, is a crucial 975 amino acid protein encoded by the human gene CHTF18, which plays a significant role in maintaining genomic stability. Structurally, CTF18 is related to the Rad24 and replication factor C (RFC) proteins and forms a unique RFC complex that operates redundantly with Rad24 during the DNA replication block checkpoint. This CTF18-RFC complex is composed of seven subunits, including the four small subunits of RFC, along with CTF18, DCC1, and CTF8, and loads the replication clamp, proliferating cell nuclear antigen (PCNA), onto DNA, facilitating DNA replication and repair processes. Proper functioning of this complex ensures DNA replication proceeds accurately and efficiently, preventing potential genomic instability that could lead to various diseases, including cancer. Anti-CTF18 antibody (B-7) serves as an invaluable tool for researchers studying the mechanisms of DNA replication and repair, as well as the broader implications of genomic fidelity in cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CTF18 Antibody (B-7) | sc-376074 | 200 µg/ml | $322.00 | |||
CTF18 Antibody (B-7): m-IgG Fc BP-HRP Bundle | sc-540506 | 200 µg Ab; 10 µg BP | $361.00 | |||
CTF18 Antibody (B-7): m-IgG1 BP-HRP Bundle | sc-542166 | 200 µg Ab; 20 µg BP | $361.00 |