Cryptosporidium parvum Antibody (7631): sc-58112

Cryptosporidium parvum Antibody (7631) is a mouse monoclonal IgG antibody that detects Cryptosporidium parvum protein by immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-Cryptosporidium parvum antibody (7631) is available as a non-conjugated format. This parasitic protozoan, belonging to the phylum Apicomplexa and subclass Coccidia, is a significant enteric pathogen responsible for cryptosporidiosis, a disease that poses a serious health risk, particularly in immunocompromised individuals. Cryptosporidium parvum protein plays a crucial role in the organism′s life cycle, facilitating invasion of host cells and evasion of immune response. Understanding Cryptosporidium parvum protein function is vital, as this knowledge contributes to pathogenicity studies and aids in developing targeted therapies and diagnostic tools. Cryptosporidium parvum oocysts are highly infectious and primarily transmitted through contaminated water, food, or fecal matter from infected hosts, making protein studies essential for effective public health interventions. In humans, infection can lead to severe gastrointestinal symptoms, including abdominal pain and profuse diarrhea, which can be particularly debilitating for those with weakened immune systems.

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Cryptosporidium parvum Antibody (7631) References:

1. Adhesion kinetics of viable Cryptosporidium parvum oocysts to quartz surfaces.  |  Kuznar, ZA. and Elimelech, M. 2004. Environ Sci Technol. 38: 6839-45. PMID: 15669347
2. Comparison of Cryptosporidium parvum development in various cell lines for screening in vitro drug testing.  |  Siripanth, C., et al. 2004. Southeast Asian J Trop Med Public Health. 35: 540-6. PMID: 15689063
3. Mucosal cytokine and antigen-specific responses to Cryptosporidium parvum in IL-12p40 KO mice.  |  Ehigiator, HN., et al. 2005. Parasite Immunol. 27: 17-28. PMID: 15813719
4. Multiple TLRs are expressed in human cholangiocytes and mediate host epithelial defense responses to Cryptosporidium parvum via activation of NF-kappaB.  |  Chen, XM., et al. 2005. J Immunol. 175: 7447-56. PMID: 16301652
5. Modeling Cryptosporidium parvum oocyst inactivation and bromate formation in a full-scale ozone contactor.  |  Tang, G., et al. 2005. Environ Sci Technol. 39: 9343-50. PMID: 16382962
6. Characterization of a factor from bovine intestine that protects against Cryptosporidium parvum infection.  |  Akili, D., et al. 2006. Vet Parasitol. 142: 168-72. PMID: 16870345
7. A potential role for interleukin-18 in inhibition of the development of Cryptosporidium parvum.  |  McDonald, V., et al. 2006. Clin Exp Immunol. 145: 555-62. PMID: 16907926
8. Cryptosporidium parvum: the contribution of Th1-inducing pathways to the resolution of infection in mice.  |  Ehigiator, HN., et al. 2007. Exp Parasitol. 115: 107-13. PMID: 16920103
9. Co-infection with Cryptosporidium parvum and Cyclospora cayetanensis in immunocompromised patients.  |  Helmy, MM., et al. 2006. J Egypt Soc Parasitol. 36: 613-27. PMID: 16927872

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Cryptosporidium parvum Antibody (7631) has 1 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Cryptosporidium parvum Antibody (7631) Specifications

Alternate Product Name: Cryptosporidium parvum

Product Clone Name: 7631

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG

Amino Acids:

Epitope Target:

Epitope Species: Cryptosporidium parvum

Product Reactivity/Detection: intact Cryptosporidium parvum oocysts

Species Reactivity/Detection: Cryptosporidium parvum

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF, IHC(P)

Vialing Information: Each vial contains 100 µg IgG in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Cryptosporidium parvum Antibody (7631): N/A