CRSP34 Antibody (40.4): sc-101187
- CRSP34 Antibody (40.4) is a mouse monoclonal mouse IgG1 κ κ provided at 50 µg/0.5 ml
- raised against recombinant CRSP34 of human origin
- recommended for detection of CRSP34 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CRSP34 Antibody (40.4). This work is in progress.
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CRSP34 Antibody (40.4) is a mouse monoclonal IgG1 antibody that detects CRSP34 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). CRSP34 is a crucial component of the coactivator complex CRSP, which plays a significant role in the regulation of transcription by mediating the interaction between transcriptional activators and RNA polymerase. CRSP34 is primarily located in the nucleus, where CRSP34 contributes to the assembly of transcriptional machinery necessary for gene expression. Nuclear localization of CRSP34 ensures efficient coordination of transcriptional processes, allowing for precise gene regulation in response to various cellular signals. CRSP34 interacts with other subunits of the CRSP complex, enhancing the overall functionality of the transcriptional machinery. Formation of complexes with other coactivators, such as ARC/DRI, further underscores CRSP34′s importance in facilitating transcriptional activation by nuclear hormone receptors and other transcription factors. CRSP34′s versatility in various tissues and essential role in transcriptional regulation make CRSP34 a valuable target for research in gene expression and cellular signaling pathways.
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CRSP34 Antibody (40.4) References:
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- Unsymmetrical aromatic disulfides as SARS-CoV-2 Mpro inhibitors: Molecular docking, molecular dynamics, and ADME scoring investigations. | Chtita, S., et al. 2022. J King Saud Univ Sci. 34: 102226. PMID: 35875823
- Electronic Structure and Magneto-Structural Correlations Study of Cu2UL Trinuclear Schiff Base Complexes: A 3d-5f-3d Case. | Meskaldji, S., et al. 2023. J Phys Chem A. 127: 1475-1490. PMID: 36749943
- Crystal structure and Hirshfeld surface analysis of a new benzimidazole compound, 3-{1-[(2-hy-droxyphen-yl)meth-yl]-1H-1,3-benzo-diazol-2-yl}phenol. | Bouhidel, Z., et al. 2024. Acta Crystallogr E Crystallogr Commun. 80: 18-21. PMID: 38312163
- The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1. | Ryu, S., et al. 1999. Nature. 397: 446-50. PMID: 9989412
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CRSP34 Antibody (40.4) | sc-101187 | 50 µg/0.5 ml | $339.00 |