CRHSP-24 Antibody (D-6): sc-393348

CRHSP-24 Antibody (D-6) is a mouse monoclonal IgG2a antibody that detects CRHSP-24 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CRHSP-24, also known as calcium-regulated heat-stable protein 24, is a serine phosphoprotein that plays a crucial role in calcium-mediated signal transduction, primarily due to phosphorylation on serine residues. CRHSP-24 is widely expressed across various tissues and is involved in critical cellular processes, including spermatogenesis regulation, where CRHSP-24 interacts with the STYX/dead phosphate protein in developing spermatids. Phosphorylation of CRHSP-24 on Ser 52 by Akt-1 in response to insulin-like growth factor 1 (IGF-1) and by RSK in response to epidermal growth factor (EGF) highlights CRHSP-24′s importance in signaling pathways that govern cell growth and differentiation. Additionally, phosphorylation on Ser 41 in the absence of IGF-1/EGF by a DYRK isoform or another proline-directed protein kinase further emphasizes CRHSP-24′s regulatory mechanisms in response to various stimuli. Anti-CRHSP-24 antibody (D-6) is an essential tool for researchers exploring CRHSP-24′s intricate roles in cellular signaling and implications in health and disease.

The preferred CRHSP-24 antibody is CRHSP-24 Antibody (A-1): sc-137072.