CPPED1 Antibody (H-11): sc-514222
- CPPED1 Antibody (H-11) is a mouse monoclonal IgG1 κ CPPED1 antibody, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 47-71 within an internal region of CPPED1 of human origin
- CPPED1 Antibody (H-11) is recommended for detection of CPPED1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-CPPED1 Antibody (H-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CPPED1 Antibody (H-11) for WB applications. These reagents are now offered in bundles with CPPED1 Antibody (H-11) (see ordering information below).
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CPPED1 Antibody (H-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects CPPED1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CPPED1 (H-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CPPED1, also known as calcineurin-like phosphoesterase domain containing 1, is a member of the metallophosphoesterase superfamily, which plays a crucial role in catalyzing a range of cellular reactions. CPPED1 is characterized by its conserved β-α-β-α-β fold structure, which is essential for enzymatic activity, as this structure houses a dimetal center vital for binding divalent metal cations, necessary cofactors for function. These metal ions are critical for CPPED1′s catalytic mechanism, influencing CPPED1′s ability to hydrolyze phosphate esters, which are important in various cellular processes, including signal transduction and metabolic regulation. The gene encoding CPPED1 is located on human chromosome 16, a region associated with several genetic disorders, highlighting CPPED1′s potential implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CPPED1 Antibody (H-11) References:
- The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy. | Bomont, P., et al. 2000. Nat Genet. 26: 370-4. PMID: 11062483
- cDNA cloning, genomic organization and expression of the novel human metallophosphoesterase gene MPPE1 on chromosome 18p11.2. | Vuoristo, JT. and Ala-Kokko, L. 2001. Cytogenet Cell Genet. 95: 60-3. PMID: 11978971
- Genetics of inflammatory bowel disease: progress and prospects. | Mathew, CG. and Lewis, CM. 2004. Hum Mol Genet. 13 Spec No 1: R161-8. PMID: 14764625
- Transactivating effect of complete S protein of hepatitis B virus and cloning of genes transactivated by complete S protein using suppression subtractive hybridization technique. | Bai, GQ., et al. 2005. World J Gastroenterol. 11: 3893-8. PMID: 15991289
- Characterization of an evolutionarily conserved metallophosphoesterase that is expressed in the fetal brain and associated with the WAGR syndrome. | Tyagi, R., et al. 2009. J Biol Chem. 284: 5217-28. PMID: 19004815
- The Rubinstein-Taybi syndrome: occurrence in two sets of identical twins. | Baraitser, M. and Preece, MA. 1983. Clin Genet. 23: 318-20. PMID: 6682729
- Rubinstein-Taybi syndrome caused by submicroscopic deletions within 16p13.3. | Breuning, MH., et al. 1993. Am J Hum Genet. 52: 249-54. PMID: 8430691
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CPPED1 Antibody (H-11) | sc-514222 | 200 µg/ml | $316.00 | |||
CPPED1 Antibody (H-11): m-IgG Fc BP-HRP Bundle | sc-527871 | 200 µg Ab; 10 µg BP | $354.00 | |||
CPPED1 Antibody (H-11): m-IgG1 BP-HRP Bundle | sc-533244 | 200 µg Ab; 20 µg BP | $354.00 | |||
CPPED1 Antibody (H-11) AC | sc-514222 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CPPED1 Antibody (H-11) HRP | sc-514222 HRP | 200 µg/ml | $316.00 | |||
CPPED1 Antibody (H-11) FITC | sc-514222 FITC | 200 µg/ml | $330.00 | |||
CPPED1 Antibody (H-11) PE | sc-514222 PE | 200 µg/ml | $343.00 | |||
CPPED1 Antibody (H-11) Alexa Fluor® 488 | sc-514222 AF488 | 200 µg/ml | $357.00 | |||
CPPED1 Antibody (H-11) Alexa Fluor® 546 | sc-514222 AF546 | 200 µg/ml | $357.00 | |||
CPPED1 Antibody (H-11) Alexa Fluor® 594 | sc-514222 AF594 | 200 µg/ml | $357.00 | |||
CPPED1 Antibody (H-11) Alexa Fluor® 647 | sc-514222 AF647 | 200 µg/ml | $357.00 | |||
CPPED1 Antibody (H-11) Alexa Fluor® 680 | sc-514222 AF680 | 200 µg/ml | $357.00 | |||
CPPED1 Antibody (H-11) Alexa Fluor® 790 | sc-514222 AF790 | 200 µg/ml | $357.00 | |||
CPPED1 (H-11) Neutralizing Peptide | sc-514222 P | 100 µg/0.5 ml | $68.00 |