cPLA2 Antibody (H-12): sc-376636
- cPLA2 Antibody (H-12) is a mouse monoclonal IgG3 λ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 721-752 at the C-terminus of cPLA2 of human origin
- recommended for detection of cytosolic PLA2 of mouse, rat and human origin by WB, IP, IF and ELISA
- See cPLA2 (4-4B-3C): sc-454 for cPLA2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for cPLA2 Antibody (H-12) for WB applications. This reagent is now offered in a bundle with cPLA2 Antibody (H-12) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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cPLA2 Antibody (H-12) is a mouse monoclonal IgG3 antibody that detects cytosolic phospholipase A2 (cPLA2) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). cPLA2 plays a crucial role in phospholipid hydrolysis, specifically targeting the sn-2 position to release arachidonic acid, a key precursor for synthesizing various eicosanoids, including prostaglandins and leukotrienes, which are significant mediators of inflammatory responses. Anti-cPLA2 antibody (H-12) enables detection in diverse cell types, such as platelets, macrophages, and monoblasts, where cPLA2 localizes in the cytosol for rapid mobilization and release of arachidonic acid in response to cellular stimuli, influencing numerous physiological and pathological processes, including inflammation, pain, and immune responses. cPLA2 (H-12) antibody serves as an essential tool for researchers investigating inflammation mechanisms and eicosanoid roles in various diseases, providing reliable detection and characterization of this vital enzyme in different biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cPLA2 Antibody (H-12) | sc-376636 | 200 µg/ml | $316.00 | |||
cPLA2 Antibody (H-12): m-IgGλ BP-HRP Bundle | sc-523028 | 200 µg Ab, 40 µg BP | $354.00 | |||
cPLA2 (H-12) Neutralizing Peptide | sc-376636 P | 100 µg/0.5 ml | $68.00 |