Molecular structure of CP 809101 hydrochloride, CAS Number: 479683-64-2
CP 809101 hydrochloride (CAS 479683-64-2)
Alternate Names:
2-[(3-Chlorophenyl)methoxy]-6-(1-pi perazinyl)pyrazine hydrochloride
Application:
CP 809101 hydrochloride is a potent and selective SR-2C agonist
CAS Number:
479683-64-2
Purity:
≥99%
Molecular Weight:
341.24
Molecular Formula:
C15H17N4OCl•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
CP 809101 hydrochloride is a research chemical primarily utilized for its activity as a selective serotonin receptor agonist in neuroscience studies. It is particularly valuable in research focused on the modulation of serotonin receptors, which are implicated in a wide range of neurological processes. Studies involving CP 809101 hydrochloride often aim to elucidate the role of these receptors in mood regulation, cognition, and neural network functioning. In certain research models, this compound is used to understand the consequences of serotonin receptor activation on behavior and physiological responses. Additionally, CP 809101 hydrochloride serves as a tool in the investigation of signal transduction pathways, providing insights into the intracellular processes that follow receptor activation and contribute to the complex mechanisms of serotonin.
CP 809101 hydrochloride (CAS 479683-64-2) References
- Evidence that the reward attenuating effect of the D1-like antagonist, SCH-23390, is not mediated by its agonist action at the 5-HT2c receptors. | Benaliouad, F., et al. 2011. Behav Brain Res. 217: 467-71. PMID: 20920533
- 5-HT2C receptors in the basolateral amygdala and dorsal striatum are a novel target for the anxiolytic and antidepressant effects of exercise. | Greenwood, BN., et al. 2012. PLoS One. 7: e46118. PMID: 23049953
- Evaluation of chemically diverse 5-HT₂c receptor agonists on behaviours motivated by food and nicotine and on side effect profiles. | Higgins, GA., et al. 2013. Psychopharmacology (Berl). 226: 475-90. PMID: 23184281
- Serotonergic hallucinogens differentially modify gamma and high frequency oscillations in the rat nucleus accumbens. | Goda, SA., et al. 2013. Psychopharmacology (Berl). 228: 271-82. PMID: 23525524
- Critical involvement of 5-HT2C receptor function in amphetamine-induced 50-kHz ultrasonic vocalizations in rats. | Wöhr, M., et al. 2015. Psychopharmacology (Berl). 232: 1817-29. PMID: 25417553
- Signal Transduction Mechanism for Serotonin 5-HT2B Receptor-Mediated DNA Synthesis and Proliferation in Primary Cultures of Adult Rat Hepatocytes. | Naito, K., et al. 2016. Biol Pharm Bull. 39: 121-9. PMID: 26567725
- 5-HT2 Receptor Regulation of Mitochondrial Genes: Unexpected Pharmacological Effects of Agonists and Antagonists. | Harmon, JL., et al. 2016. J Pharmacol Exp Ther. 357: 1-9. PMID: 26787771
- Lorcaserin and CP-809101 reduce motor impulsivity and reinstatement of food seeking behavior in male rats: Implications for understanding the anti-obesity property of 5-HT2C receptor agonists. | Higgins, GA., et al. 2016. Psychopharmacology (Berl). 233: 2841-56. PMID: 27241709
- Loss of GluN2D subunit results in social recognition deficit, social stress, 5-HT2C receptor dysfunction, and anhedonia in mice. | Yamamoto, H., et al. 2017. Neuropharmacology. 112: 188-197. PMID: 27480795
- Studies To Examine Potential Tolerability Differences between the 5-HT2C Receptor Selective Agonists Lorcaserin and CP-809101. | Higgins, GA., et al. 2017. ACS Chem Neurosci. 8: 1074-1084. PMID: 28338324
- Role of the serotonergic system in urethral continence reflexes during sneezing in rats. | Suzuki, T., et al. 2018. Am J Physiol Renal Physiol. 315: F79-F85. PMID: 29442547
- Stimulation of 5-HT2C serotonin receptor subtype in the hypothalamic arcuate nuclei (ARC) increases the cytochrome P450 activity in the liver. | Bromek, E., et al. 2019. Pharmacol Rep. 71: 1210-1212. PMID: 31671379
- A claustrum in reptiles and its role in slow-wave sleep. | Norimoto, H., et al. 2020. Nature. 578: 413-418. PMID: 32051589
- Effects of 5-HT2C receptor modulation and the NA reuptake inhibitor atomoxetine in tests of compulsive and impulsive behaviour. | Higgins, GA., et al. 2020. Neuropharmacology. 170: 108064. PMID: 32222404
- Developmental programming of appetite and growth in male rats increases hypothalamic serotonin (5-HT)5A receptor expression and sensitivity. | Wargent, ET., et al. 2020. Int J Obes (Lond). 44: 1946-1957. PMID: 32719434
Activator of:
SR-2C.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CP 809101 hydrochloride, 10 mg | sc-205277 | 10 mg | $132.00 | |||
| US: Only available in the US | ||||||
CP 809101 hydrochloride, 50 mg | sc-205277A | 50 mg | $559.00 | |||
| US: Only available in the US | ||||||