COX5b Antibody (B-2): sc-374417
- COX5b Antibody (B-2) is a mouse monoclonal IgG1 κ, cited in 8 publications, provided at 200 µg/ml
- raised against amino acids 35-129 mapping at the C-terminus of COX5b of human origin
- recommended for detection of COX5b of mouse, rat, human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for COX5b Antibody (B-2) for WB and IHC(P) applications. These reagents are now offered in bundles with COX5b Antibody (B-2) (see ordering information below).
COX5b Antibody (B-2) is a mouse monoclonal IgG1 antibody that detects COX5b in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). COX5b is a crucial component of the cytochrome c oxidase (COX) complex, which plays a vital role in cellular respiration by facilitating the final step of the electron transport chain. COX5b is located in the inner mitochondrial membrane, where COX5b participates in the conversion of oxygen and hydrogen into water, a process essential for maintaining the proton gradient necessary for ATP production. COX5b expression is upregulated under hypoxic conditions to enhance the efficiency of the COX apoenzyme, thereby ensuring that cells can continue to generate energy even when oxygen levels are low. COX5b′s ability to adapt to varying oxygen levels highlights COX5b′s significance in cellular metabolism and energy homeostasis, making COX5b a valuable target for research in metabolic disorders and mitochondrial dysfunction. Anti-COX5b antibody (B-2) is an essential tool for researchers investigating the dynamics of mitochondrial function and the role of cytochrome c oxidase in various physiological and pathological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
COX5b Antibody (B-2) | sc-374417 | 200 µg/ml | $322.00 | |||
COX5b Antibody (B-2): m-IgG Fc BP-HRP Bundle | sc-540450 | 200 µg Ab; 10 µg BP | $361.00 | |||
COX5b Antibody (B-2): m-IgG1 BP-HRP Bundle | sc-542131 | 200 µg Ab; 20 µg BP | $361.00 |