Coronavirus nucleocapsid Antibody (CCV2-2): sc-66012

Coronavirus nucleocapsid Antibody (CCV2-2) is a mouse monoclonal IgG1 antibody that detects the nucleocapsid protein of Coronavirus by western blotting (WB) and immunofluorescence (IF). Anti-Coronavirus nucleocapsid antibody (CCV2-2) is available in a non-conjugated form, specifically designed for researchers studying the intricate biology of Coronaviruses. The nucleocapsid protein plays a crucial role in the viral life cycle, as this protein is essential for packaging the viral RNA genome and forming the viral envelope. The nucleocapsid protein not only protects viral RNA from degradation but also facilitates the assembly and budding of new virions, making this protein a key target for therapeutic interventions and vaccine development. Coronaviruses, belonging to the family Coronaviridae, are enveloped viruses characterized by their positive-sense single-stranded RNA genome and helical symmetry, which gives these viruses a crown-like appearance under an electron microscope. These viruses primarily infect the upper respiratory and gastrointestinal tracts of mammals and birds, with several strains known to infect humans, including those responsible for common colds and more severe diseases like SARS-CoV, which can lead to significant respiratory complications. Understanding nucleocapsid protein function is vital for developing effective strategies to combat Coronavirus infections and mitigate their impact on public health.

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Coronavirus nucleocapsid Antibody (CCV2-2) References:

1. A review of coronavirus infection in the central nervous system of cats and mice.  |  Foley, JE. and Leutenegger, C. 2001. J Vet Intern Med. 15: 438-44. PMID: 11596730
2. Proteomic analysis on structural proteins of Severe Acute Respiratory Syndrome coronavirus.  |  Ying, W., et al. 2004. Proteomics. 4: 492-504. PMID: 14760722
3. HIV infection in kidney transplant recipients.  |  Ribot, S. and Eslami, HH. 1992. N J Med. 89: 597-9. PMID: 1513506
4. Detection of human coronavirus NL63 in young children with bronchiolitis.  |  Ebihara, T., et al. 2005. J Med Virol. 75: 463-5. PMID: 15648061
5. Severe acute respiratory syndrome associated coronavirus is detected in intestinal tissues of fatal cases.  |  Shi, X., et al. 2005. Am J Gastroenterol. 100: 169-76. PMID: 15654797
6. Association between a novel human coronavirus and Kawasaki disease.  |  Esper, F., et al. 2005. J Infect Dis. 191: 499-502. PMID: 15655771
7. Receptor-independent infection of murine coronavirus: analysis by spinoculation.  |  Watanabe, R., et al. 2006. J Virol. 80: 4901-8. PMID: 16641281
8. Genetic variability of human coronavirus OC43-, 229E-, and NL63-like strains and their association with lower respiratory tract infections of hospitalized infants and immunocompromised patients.  |  Gerna, G., et al. 2006. J Med Virol. 78: 938-49. PMID: 16721849
9. Entry of coronavirus into primate CNS following peripheral infection.  |  Cabirac, GF., et al. 1994. Microb Pathog. 16: 349-57. PMID: 7815918

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Coronavirus nucleocapsid Antibody (CCV2-2) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Coronavirus nucleocapsid Antibody (CCV2-2) Specifications

Alternate Product Name: Coronavirus nucleocapsid

Product Clone Name: CCV2-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Coronavirus nucleocapsid

Epitope Species: FIPV, CCV and TGEV Coronavirus

Product Reactivity/Detection: nucleocapsid

Species Reactivity/Detection: Coronavirus

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Coronavirus nucleocapsid Antibody (CCV2-2): N/A