COPE Antibody (E-1): sc-166046
- COPE Antibody (E-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 261-293 near the C-terminus of COPE of human origin
- recommended for detection of COPE of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and canine and bovine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for COPE Antibody (E-1) for WB and IHC(P) applications. These reagents are now offered in bundles with COPE Antibody (E-1) (see ordering information below).
COPE Antibody (E-1) is a mouse monoclonal IgG1 antibody that detects COPE in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). COPE, or coatomer protein complex subunit epsilon, plays a crucial role in the formation of COPI-coated vesicles, which are essential for retrograde transport from the Golgi apparatus back to the endoplasmic reticulum (ER) as well as intra-Golgi transport. COPE (E-1) antibody targets a protein primarily located in the cytoplasm that is integral to maintaining cellular homeostasis by facilitating the recycling of proteins and lipids, thus ensuring that the ER and Golgi apparatus function efficiently. COPE monoclonal antibody (E-1) recognizes a protein vital for the secretion of proteins and the overall trafficking of membrane-bound proteins, which are critical for various cellular processes, including cell signaling and metabolism. Disruptions in COPE function can lead to significant cellular dysfunction and are implicated in various diseases, making anti-COPE antibody (E-1) an invaluable tool for researchers studying membrane trafficking and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
COPE Antibody (E-1) | sc-166046 | 200 µg/ml | $316.00 | |||
COPE Antibody (E-1): m-IgG Fc BP-HRP Bundle | sc-539996 | 200 µg Ab; 10 µg BP | $354.00 | |||
COPE Antibody (E-1): m-IgG1 BP-HRP Bundle | sc-541834 | 200 µg Ab; 20 µg BP | $354.00 | |||
COPE (E-1) Neutralizing Peptide | sc-166046 P | 100 µg/0.5 ml | $68.00 |