Molecular structure of Cochlioquinone B, CAS Number: 32450-26-3
Cochlioquinone B (CAS 32450-26-3)
Application:
Cochlioquinone B is an NADH ubiquinonereductase inhibitor and a phytotoxic agent
CAS Number:
32450-26-3
Purity:
>99%
Molecular Weight:
472.6
Molecular Formula:
C28H40O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Cochlioquinone B, the minor component of a bioactive pigment isolated from Bipolaris leersia, is an NADH ubiquinonereductase inhibitor and a phytotoxic agent inhibiting root growth. It is closely related to Cochlioquinone A that inhibits diacylglycerol acyltransferase and exhdibits anti-angiogenic and nematocidal activity. Cochlioquinones have been recently shown to be antagonists of the human chemokine receptor CCR5 in human immunodeficiency virus type 1 (HIV-1).
Cochlioquinone B (CAS 32450-26-3) References
- Cochlioquinone A1, a new anti-angiogenic agent from Bipolaris zeicola. | Jung, HJ., et al. 2003. Bioorg Med Chem. 11: 4743-7. PMID: 14556789
- Inhibitory activity of diacylglycerol acyltransferase by cochlioquinones A and A1. | Lee, HB., et al. 2003. J Antibiot (Tokyo). 56: 967-9. PMID: 14763563
- The sperm penetration test (P-test) can predict fecundability in the male partner from infertile couples. | Bostofte, E., et al. 1992. Andrologia. 24: 125-9. PMID: 1503248
- Genome-based mining of new antimicrobial meroterpenoids from the phytopathogenic fungus Bipolaris sorokiniana strain 11134. | Han, J., et al. 2020. Appl Microbiol Biotechnol. 104: 3835-3846. PMID: 32215711
- Cochlioquinone derivative CoB1 induces cytostatic autophagy in lung cancer through miRNA-125b and Foxp3. | Xu, N., et al. 2021. Phytomedicine. 93: 153742. PMID: 34624808
Inhibitor of:
Angiogenesis, and DGAT.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cochlioquinone B, 500 µg | sc-202110 | 500 µg | $246.00 |