CMV gB Antibody (1.B.222) is a mouse monoclonal IgG1 antibody that detects CMV gB of cytomegalovirus (CMV) by western blotting (WB) and immunofluorescence (IF). CMV gB, or CMV glycoprotein B, plays a crucial role in the viral life cycle as CMV gB is essential for CMV infectivity, facilitating virus entry into host cells by mediating fusion between the viral envelope and host cell membrane. This function is particularly important because CMV gB allows CMV to establish infection and persist within the host, contributing to viral evasion of the immune system and dormancy for extended periods. The immunogenic nature of CMV gB also makes CMV gB a target for neutralizing antibodies, which are vital for developing effective vaccines and therapeutic strategies against CMV infections, especially in immunocompromised individuals who are at higher risk for severe disease. Anti-CMV gB antibody (1.B.222) is therefore an invaluable tool for researchers studying CMV pathogenesis and immune responses, providing insights that could lead to improved clinical outcomes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CMV gB Antibody (1.B.222) | sc-70942 | 100 µg/ml | $316.00 |