CMPD1 CAS: 41179-33-3
MF: C22H20FNO2
MW: 349.4
A tubulin inhibitor.

CMPD1 (CAS 41179-33-3)

CMPD1 | CAS 41179-33-3 is rated 2.3 out of 5 by 3.
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Application: A tubulin inhibitor
CAS Number: 41179-33-3
Molecular Weight: 349.4
Molecular Formula: C22H20FNO2
* Refer to Certificate of Analysis for lot specific data (including water content).
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CMPD1 Inhibits tubulin polymerisation.


References

1. Lukas, S.M. et al. 2004. Biochemistry. 43(31): 9950-9960. PMID: 15287722
2. Davidson, W. et al. 2004. Biochemistry. 43(37): 11658-11671. PMID: 15362850
3. Yuan, J. et al. 2010. PLoS ONE. 5(6): e11247. PMID: 20596525

Physical State :
Solid
Solubility :
Soluble in ethanol (100 mM), and DMSO (100 mM).
Storage :
Store at 4° C
Melting Point :
233.01° C (Predicted)
Boiling Point :
584.96° C at 760 mmHg (Predicted)
Density :
1.23 g/cm3 (Predicted)
Refractive Index :
n20D 1.63 (Predicted)
Ki Data :
MAPKAPK-2: Ki= 0.33 µM
pK Values :
pKa: 10.11 (Predicted), pKb: 1.7 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
11382492
MDL Number :
MFCD08703098
SMILES :
C1=CC=C(C(=C1)C2=CC=C(C=C2)CCCC(=O)NC3=CC=C(C=C3)O)F

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Certificate of Analysis

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CMPD1  Product Citations

See how others have used CMPD1. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 31936572  Cells. 9:

Citations 1 to 1 of 1 total
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Rated 1 out of 5 by from CMPD1 does not inhibit MK2 in tumor cells CMPD1 does not inhibit MK2 in tumor cells http://www.nature.com/articles/cddiscovery201528
Date published: 2015-10-12
Rated 1 out of 5 by from compound toxic compound toxic
Date published: 2015-10-12
Rated 5 out of 5 by from Hossain et al Hossain et al. (PubMed ID 22511273) found that CMPD1 inhibited MK2 decreased Krox-20-positive Schwann cells and expression of myelin proteins MBP and MAG in rat neuronal cultures. -SCBT Publication Review
Date published: 2015-03-03
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