CLEC-16A Antibody (H-4): sc-398516

CLEC-16A Antibody (H-4) is a mouse monoclonal IgM antibody that detects CLEC-16A of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-CLEC-16A antibody (H-4) is available as the non-conjugated form. CLEC-16A, also known as C-type lectin domain family 16, member A, plays a crucial role in the immune system, particularly in regulating innate immunity. CLEC-16A is primarily expressed in dendritic cells, B lymphocytes, and natural killer cells, where CLEC-16A contributes to pathogen recognition and immune response modulation. CLEC-16A is involved in interactions with specific proteins essential for immune signaling pathways, including those mediating responses to infections and inflammation. Defects in CLEC-16A have been linked to insulin-dependent diabetes mellitus and primary adrenal insufficiency, highlighting CLEC-16A′s importance in maintaining immune homeostasis. Multiple isoforms of CLEC-16A arise from alternative splicing, which may influence functional diversity and interactions within the immune system.

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CLEC-16A Antibody (H-4) References:

1. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.  |  Nakajima, D., et al. 2002. DNA Res. 9: 99-106. PMID: 12168954
2. A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.  |  Hakonarson, H., et al. 2007. Nature. 448: 591-4. PMID: 17632545
3. Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency.  |  Skinningsrud, B., et al. 2008. J Clin Endocrinol Metab. 93: 3310-7. PMID: 18593762
4. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.  |  Nagase, T., et al. 1997. DNA Res. 4: 141-50. PMID: 9205841

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CLEC-16A Antibody (H-4) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-CLEC-16A Antibody (H-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CLEC-16A Antibody (H-4) Specifications

Alternate Product Name: CLEC-16A

Product Clone Name: H-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 61-360

Epitope Target: CLEC-16A

Epitope Species: human

Product Reactivity/Detection: CLEC-16A

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for CLEC-16A Antibody (H-4): N/A