CKR-4 Antibody (G-2): sc-377357
- CKR-4 Antibody (G-2) is a mouse monoclonal IgG2a κ CKR-4 antibody provided at 200 µg/ml
- raised against amino acids 313-360 of CKR-4 of human origin
- CKR-4 Antibody (G-2) is recommended for detection of CKR-4 of human origin by WB, IP, IF and ELISA
- Anti-CKR-4 Antibody (G-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CKR-4 Antibody (G-2) for WB applications. These reagents are now offered in bundles with CKR-4 Antibody (G-2) (see ordering information below).
CKR-4 Antibody (G-2) is a mouse monoclonal IgG2a kappa light chain antibody that detects CKR-4 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CKR-4 (G-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CKR-4, also known as C-C chemokine receptor type 4 or CCR4, is a 360 amino acid multi-pass membrane protein that plays a crucial role in the immune response by acting as a high-affinity receptor for C-C type chemokines. CCR4 is predominantly expressed in peripheral blood leukocytes and thymus tissue, where CCR4 is involved in the chemotaxis of T cells and monocytes to sites of inflammation. CCR4 is also implicated in the survival of hippocampal neurons, highlighting CCR4′s significance in neuroprotection and potential therapeutic targets in neurodegenerative diseases. CCR4′s interaction with specific chemokines not only facilitates immune cell migration but also suggests a role in modulating inflammatory responses, making CCR4 a vital component in both immune regulation and neuronal health.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CKR-4 Antibody (G-2) | sc-377357 | 200 µg/ml | $322.00 | |||
CKR-4 Antibody (G-2): m-IgGκ BP-HRP Bundle | sc-523292 | 200 µg Ab, 40 µg BP | $361.00 | |||
CKR-4 Antibody (G-2): m-IgG2a BP-HRP Bundle | sc-546153 | 200 µg Ab; 10 µg BP | $361.00 | |||
CKR-4 Antibody (G-2) AC | sc-377357 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CKR-4 Antibody (G-2) HRP | sc-377357 HRP | 200 µg/ml | $322.00 | |||
CKR-4 Antibody (G-2) FITC | sc-377357 FITC | 200 µg/ml | $336.00 | |||
CKR-4 Antibody (G-2) PE | sc-377357 PE | 200 µg/ml | $349.00 | |||
CKR-4 Antibody (G-2) Alexa Fluor® 488 | sc-377357 AF488 | 200 µg/ml | $364.00 | |||
CKR-4 Antibody (G-2) Alexa Fluor® 546 | sc-377357 AF546 | 200 µg/ml | $364.00 | |||
CKR-4 Antibody (G-2) Alexa Fluor® 594 | sc-377357 AF594 | 200 µg/ml | $364.00 | |||
CKR-4 Antibody (G-2) Alexa Fluor® 647 | sc-377357 AF647 | 200 µg/ml | $364.00 | |||
CKR-4 Antibody (G-2) Alexa Fluor® 680 | sc-377357 AF680 | 200 µg/ml | $364.00 | |||
CKR-4 Antibody (G-2) Alexa Fluor® 790 | sc-377357 AF790 | 200 µg/ml | $364.00 |