Molecular structure of Cilengitide, CAS Number: 188968-51-6
Cilengitide (CAS 188968-51-6)
Alternate Names:
EMD121974,cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-N-methyl-L-valyl)
CAS Number:
188968-51-6
Molecular Weight:
588.7
Molecular Formula:
C27H40N8O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Cilengitide (CAS 188968-51-6) References
- Cilengitide inhibits metastatic bone colonization in a nude rat model. | Bretschi, M., et al. 2011. Oncol Rep. 26: 843-51. PMID: 21725616
- Cilengitide induces autophagy-mediated cell death in glioma cells. | Lomonaco, SL., et al. 2011. Neuro Oncol. 13: 857-65. PMID: 21788343
- Cilengitide targets pediatric glioma and neuroblastoma cells through cell detachment and anoikis induction. | Leblond, P., et al. 2013. Anticancer Drugs. 24: 818-25. PMID: 23728220
- In vitro study of combined cilengitide and radiation treatment in breast cancer cell lines. | Lautenschlaeger, T., et al. 2013. Radiat Oncol. 8: 246. PMID: 24153102
- Effects of cilengitide in osteoclast maturation and behavior. | Chillà, A., et al. 2015. Exp Cell Res. 337: 68-75. PMID: 26209605
- Cilengitide restrains the osteoclast-like bone resorbing activity of myeloma plasma cells. | Tucci, M., et al. 2016. Br J Haematol. 173: 59-69. PMID: 26728969
- Cilengitide Inhibits Neovascularization in a Rabbit Abdominal Aortic Plaque Model by Impairing the VEGF Signaling. | Zhu, F., et al. 2021. Biomed Res Int. 2021: 5954757. PMID: 34888383
- Cilengitide, an αvβ3-integrin inhibitor, enhances the efficacy of anti-programmed cell death-1 therapy in a murine melanoma model. | Pan, X., et al. 2022. Bioengineered. 13: 4557-4572. PMID: 35142593
- Combination Effect of Cilengitide with Erlotinib on TGF-β1-Induced Epithelial-to-Mesenchymal Transition in Human Non-Small Cell Lung Cancer Cells. | Jeong, J. and Kim, J. 2022. Int J Mol Sci. 23: PMID: 35408781
- Cilengitide inhibits osteoclast adhesion through blocking the αvβ3-mediated FAK/Src signaling pathway. | Guo, DY., et al. 2023. Heliyon. 9: e17841. PMID: 37539209
Inhibitor of:
ADAM18, BC049730, C8γ, CD155 (PVR; polio virus receptor), Cd302, CD9P-1, CEACAM16, CEACAM2, CERCAM, CLEC-14A, COL4A1, E130203B14Rik, EDIL3, EG210155, EG384813, EMID1, EMILIN-2, F-Spondin, Fibronectin, FREM2, HEG1, hemicentin-2, Intectin, Integrin, Integrin α11, Integrin α3, Integrin α6, Integrin α7, Integrin α9, Integrin αE, Integrin αL, Integrin αV, Integrin αVIa, Integrin αVIb, Integrin β1, Integrin β3, Integrin β4, Integrin β5, Integrin βId, Integrin alpha IIb, ITBA1, ITFG1, ITFG3, Kindlin-3, Laminin β-1, Laminin β-4, Laminin γ-3, LOC150356, LOXL2, Microfibril associated protein (MFAP), Multimerin-2, nov, otoancorin, P1 Adhesion, PCDHA11, PCDHGB1, PEDF, Periostin, Pinch-1, Podocan, PP2A-Aα, Proliferin-4, Psg16, Punc, RGMa, robo4, Ruvbl2, SPARC, Spondin (SPON), TEM8, Tenascin, Tenascin-C, Tensin3, Thrombospondin 4, TIMP-1, Vitronectin, VWA5B1, VWA5B2, VWA8, and WARP.Activator of:
Cas-L, CD99, ephrin-A2, FSD1, Integrin α1, Integrin α2, Integrin α8, Integrin αD, Integrin αX, Integrin β6, Integrin X, LTBP-4, Pinch-2, and PLVAP/PV1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cilengitide, 5 mg | sc-507335 | 5 mg | $215.00 |