Chymotrypsin Antibody (602): sc-59483
- Chymotrypsin Antibody (602) is a mouse monoclonal IgG3 Chymotrypsin antibody provided at 100 µg/ml
- raised against full length Chymotrypsin of human origin
- recommended for detection of Chymotrypsin C of mouse, rat and human origin by WB, IP and ELISA; non cross-reactive with human pancreatic trypsin
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Chymotrypsin Antibody (602). This work is in progress.
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Chymotrypsin Antibody (602) is a mouse monoclonal IgG3 antibody that detects Chymotrypsin protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-Chymotrypsin antibody (602) is available as the non-conjugated form. Chymotrypsin, a serine protease, plays a crucial role in the digestive system by catalyzing the hydrolysis of peptide bonds, particularly those adjacent to aromatic amino acids such as tyrosine, tryptophan, and phenylalanine. This enzymatic activity is vital for proper protein digestion in the small intestine, facilitating nutrient absorption and overall metabolic health. Chymotrypsin is synthesized in the pancreas as an inactive precursor known as chymotrypsinogen, which undergoes proteolytic activation to form the active enzyme composed of three polypeptide chains linked by disulfide bonds. Precise regulation of Chymotrypsin activity is essential, as uncontrolled proteolysis can lead to tissue damage and various gastrointestinal disorders. Chymotrypsin (602) monoclonal antibody serves as an invaluable tool for researchers studying digestive processes, enzyme regulation, and related pathologies, providing insights into the functional dynamics of this important protease.
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Chymotrypsin Antibody (602) References:
- Poly(ethylene glycol)-alpha-chymotrypsin complex catalytically active in anhydrous isooctane. | Murakami, Y. and Hirata, A. 1999. J Biosci Bioeng. 88: 441-3. PMID: 16232642
- Enhanced thermostability of alpha-chymotrypsin enclosed in inorganic microcapsules. | Matsumoto, M. and Kondo, K. 2001. J Biosci Bioeng. 92: 197-9. PMID: 16233085
- Substrate monolayers as electrochemical sensing elements for alpha-chymotrypsin. | Kitano, H., et al. 2002. J Colloid Interface Sci. 250: 134-41. PMID: 16290644
- Study on osmotic pressures for aqueous lysozyme and alpha-chymotrypsin-electrolyte solutions with two Yukawa potentials. | Lin, YZ., et al. 2002. J Colloid Interface Sci. 251: 256-62. PMID: 16290728
- Contrasting effects of exterior and interior hydrophobic moieties in the complexation of amino acid functionalized gold clusters with alpha-chymotrypsin. | You, CC., et al. 2005. Org Lett. 7: 5685-8. PMID: 16321022
- A self-stabilized model of the chymotrypsin catalytic pocket. The energy profile of the overall catalytic cycle. | Hudáky, P. and Perczel, A. 2006. Proteins. 62: 749-59. PMID: 16358328
- [The volume and structure of the chymotrypsin active site]. | Kostetskiĭ, PV. 2005. Biofizika. 50: 993-7. PMID: 16358776
- Chymotrypsin inhibitory triterpenoids from Silybum marianum. | Ahmed, E., et al. 2006. Chem Pharm Bull (Tokyo). 54: 103-6. PMID: 16394559
- Reversible regulation of chymotrypsin activity using negatively charged gold nanoparticles featuring malonic acid termini. | Simard, JM., et al. 2005. Med Chem. 1: 153-7. PMID: 16787310
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Chymotrypsin Antibody (602) | sc-59483 | 100 µg/ml | $316.00 |