CHD6 Antibody (2174C2a) is a mouse monoclonal IgG1 antibody that detects CHD6 in human samples through western blotting (WB) and immunoprecipitation (IP) applications. CHD6, or chromodomain-helicase-DNA-binding protein 6, is a crucial 2,715 amino acid protein encoded by the human gene CHD6, belonging to the Snf2/Rad54 helicase family. Anti-CHD6 antibody (2174C2a) recognizes a protein that plays a significant role in chromatin remodeling, which is essential for regulating gene expression and maintaining genomic stability. CHD6 contains two chromodomains, an ATP-binding helicase domain, and a C-terminal helicase domain, allowing CHD6 to interact with DNA and remodel chromatin structures effectively. The chromodomains, which are highly conserved across various species, facilitate the recognition of specific histone modifications, thereby influencing the accessibility of DNA for transcription and repair processes. Understanding the function of CHD6 is vital, as dysregulation of chromatin remodeling can lead to various diseases, including cancer. CHD6 monoclonal antibody (2174C2a) serves as an invaluable tool for researchers investigating the intricate mechanisms of chromatin dynamics and their implications in cellular processes.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CHD6 Antibody (2174C2a) | sc-81066 | 100 µg/ml | $333.00 |