CGP 71683 hydrochloride CAS: 192322-50-2
MF: C26H29N5O2S•HCl
MW: 512.07
A potent non-peptide NPY5-R antagonist.

CGP 71683 hydrochloride (CAS 192322-50-2)

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Application: CGP 71683 hydrochloride is a potent non-peptide NPY5-R antagonist
CAS Number: 192322-50-2
Molecular Weight: 512.07
Molecular Formula: C26H29N5O2S•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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CGP 71683 hydrochloride is a selective and potent non-peptide NPY5-R antagonist. This compound displays > 1000-fold selectivity over NPY1-R,NPY2-R and NPY4-R receptors; IC50 values are 1.4, 2765, 7187 and 5637 nM at cloned rat NPY5-R, NPY1-R, NPY2-R and NPY4-R respectively.


References

1. Criscione, L., et al. 1998. J. Clin. Invest. 102: 2136-2145.
2. Dumont, Y., et al. 2000. Can. J. Physiol. Pharmacol. 78: 116-125.
3. Lecklin, A., et al. 2002. Br. J. Pharmacol. 135: 2029-2037.

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM).
Storage :
Desiccate at 4° C
Boiling Point :
747.2° C at 760 mmHg (Predicted)
Refractive Index :
n20D ~1.67 (Predicted)
IC50 :
NPY Y5 receptor: IC50 = 1.4 nM (cloned rat); NPY Y1 receptor: IC50 = 2.77 µM (cloned rat); NPY Y4 receptor: IC50 = 5.64 µM (cloned rat); NPY Y2 receptor: IC50 = 7.19 µM (cloned rat)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9849276
MDL Number :
MFCD07783999
SMILES :
C1CC(CCC1CNC2=NC3=CC=CC=C3C(=N2)N)CNS(=O)(=O)C4=CC=CC5=CC=CC=C54.Cl

Download SDS (MSDS)

Certificate of Analysis

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Could you please provide quote for 8 grams (bulk order) of CGP 71683 hydrochloride.

Asked by: Rudyg
Thank you for your question. Please contact us to inquire about the availability to provide this chemical in a bulk quantity and to request a quote. Please call our Special Orders Department toll-free at (800) 457-3801 option 2, or e-mail <[email protected]>.
Answered by: Technical Support
Date published: 2017-09-14
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