Anti-CENP-H Antibody (G-9) is a mouse monoclonal IgG2a κ CENP-H antibody, cited in 1 publications, provided at 200 µg/ml
raised against amino acids 1-247 representing full length CENP-H of human origin
CENP-H Antibody (G-9) is recommended for detection of CENP-H of human origin by WB, IP, IF, IHC(P) and ELISA
Anti-CENP-H Antibody (G-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of CENP-H (G-9): sc-365222.
m-IgG Fc BP-HRP is the preferred secondary detection reagent for CENP-H Antibody (G-9) for WB and IHC(P) applications. This reagent is now offered in a bundle with CENP-H Antibody (G-9) (see ordering information below).
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CENP-H Antibody (G-9) is a high quality monoclonal CENP-H antibody (also designated CENP-H antibody) suitable for the detection of the CENP-H protein of human origin. CENP-H Antibody (G-9) is available as both the non-conjugated anti-CENP-H antibody form, as well as multiple conjugated forms of anti-CENP-H antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. A replicated chromosome includes two kinetochores that control chromosome segregation during mitosis. Both centromere proteins CENP-B and CENP-H are contained in the centromeric heterochromatin between kinetochores, and are involved in maintaining sister chromatid cohesion. The highly dispersed CENP-B promotes and maintaines the joining of DNA satellites in the centromere. CENP-B targets centromeric a-DNA and protects it from digestion by nucleases as well as preventing DNAse or restriction enzyme digestion from affecting the morphology of centromeres. CENP-H contains a coiled-coil structure and a nuclear localization signal. CENP-H is specifically and constitutively localized to kinetochores and plays a role in the organization and function of kinetochores throughout the cell cycle.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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