Cdc25B Antibody (DCS-164): sc-65504

Cdc25B Antibody (DCS-164) is a mouse monoclonal IgG1 antibody that detects Cdc25B in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cdc25B plays a crucial role in the regulation of the cell cycle, particularly in the transition from G2 phase to mitosis, by acting as a phosphatase that dephosphorylates and activates the Cdc2/cyclin B complex. This activation is essential for proper progression of mitosis, allowing cells to enter the mitotic phase at the right time, ensuring accurate chromosome segregation and cell division. Dysregulation of Cdc25B can lead to uncontrolled cell proliferation and has been implicated in various cancers, making Cdc25B a significant target for therapeutic intervention. The Cdc25 family of proteins, including Cdc25B, is characterized by their ability to interact with other regulatory proteins, and their activity is tightly controlled by phosphorylation and dephosphorylation events, highlighting the importance of post-translational modifications in cell cycle regulation. Anti-Cdc25B antibody (DCS-164) serves as an invaluable tool for researchers studying cell cycle dynamics and the molecular mechanisms underlying cell division.

The preferred Cdc25B antibody is Cdc25B Antibody (DCS-162): sc-56266.