CD9 Antibody (KMC8.8): sc-18869

CD9 Antibody (KMC8.8) is a rat monoclonal IgG2a antibody raised against BMS2 murine bone marrow stromal cells, reactive with mouse species, and validated for applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), flow cytometry (FCM), and immunohistochemistry. CD9, a member of the tetraspanin family, is a type IV transmembrane glycoprotein characterized by its four transmembrane domains and two extracellular loops, a structural configuration that is critical for its biological functions. This distinctive structure facilitates the formation of tetraspanin-enriched microdomains (TEMs) on the cell surface, which serve as platforms for protein-protein interactions and cellular signaling. CD9 is widely expressed on the surface of various cell types, including pre-B cells, eosinophils, basophils, activated T cells, and platelets, and plays a crucial role in mediating cell adhesion, migration, and intercellular communication. CD9′s structural properties enable association with integrins and other transmembrane proteins, influencing signal transduction pathways essential for processes such as immune response, tissue regeneration, and hemostasis. In platelets, CD9 is a major component of the cell surface and contributes to aggregation and clot formation, underscoring CD9′s importance in vascular biology. CD9 is also implicated in hematological malignancies, being expressed on most non-T acute lymphoblastic leukemia cells and some acute myeloid and chronic lymphoid leukemias, making CD9 a valuable marker in diagnostic and therapeutic research. Anti-CD9 antibody (KMC8.8) is available in non-conjugated and conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and Alexa Fluor® options, providing researchers with a versatile tool for in-depth exploration of CD9′s structure-function relationships and roles in cellular and pathological contexts.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CD9 Antibody (KMC8.8) has 32 citations in a variety of scientific publications.

Primary antibodies like Anti-CD9 Antibody (KMC8.8) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CD9 Antibody (KMC8.8) Specifications

Alternate Product Name: CD9

Product Clone Name: KMC8.8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: CD9

Epitope Species: murine

Product Reactivity/Detection: CD9

Species Reactivity/Detection: mouse

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), FCM

Vialing Information: Each vial contains 200 µg IgG_2a in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 32 citations in various scientific publications

Available Conjugates/Forms for CD9 Antibody (KMC8.8): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, L: Azide-Free, PE: Phycoerythrin

The preferred CD9 antibody is CD9 Antibody (C-4): sc-13118.