CD74 Antibody (A-6): sc-166047
- CD74 Antibody (A-6) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 17-296 mapping at the C-terminus of CD74 of human origin
- recommended for detection of CD74 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See CD74 (LN-2): sc-6262 for CD74 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG1 BP-HRP is the preferred secondary detection reagent for CD74 Antibody (A-6) for WB and IHC(P) applications. This reagent is now offered in a bundle with CD74 Antibody (A-6) (see ordering information below).
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CD74 Antibody (A-6) is a mouse monoclonal IgG1 antibody that detects CD74 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CD74, also known as the invariant chain, plays a crucial role in the immune system by regulating the loading of peptides onto major histocompatibility complex class II (MHC II) molecules, which are essential for presenting antigens to T lymphocytes. This process is vital for initiating adaptive immune responses, as CD74 allows the immune system to recognize and respond to pathogens effectively. CD74 is predominantly expressed in B lymphocytes and is also found in a subset of T lymphocytes, highlighting CD74′s importance in both humoral and cellular immunity. CD74 expression on these immune cells not only facilitates the proper functioning of MHC II but also serves as a marker for certain immune cell populations, making anti-CD74 antibody (A-6) an invaluable tool for researchers studying immune responses and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD74 Antibody (A-6) | sc-166047 | 200 µg/ml | $322.00 | |||
CD74 Antibody (A-6): m-IgG1 BP-HRP Bundle | sc-542656 | 200 µg Ab; 20 µg BP | $361.00 |