CD68 Antibody (B-7): sc-514937
- CD68 Antibody (B-7) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 332-354 at the C-terminus of CD68 of human origin
- recommended for detection of CD68 of human origin by WB, IP, IF, IHC(P) and ELISA
- See CD68 (KP1): sc-20060 for CD68 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG3 BP-HRP is the preferred secondary detection reagent for CD68 Antibody (B-7) for WB and IHC(P) applications. This reagent is now offered in a bundle with CD68 Antibody (B-7) (see ordering information below).
QUICK LINKS
SEE ALSO...
CD68 Antibody (B-7) is a mouse monoclonal IgG3 antibody that detects CD68 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). CD68 is a member of a family of acidic, highly glycosylated lysosomal glycoproteins, which also includes lamp-1 and lamp-2, and plays a crucial role in the immune system. CD68 is primarily located in cytoplasmic granules and the cytoplasm of various non-hematopoietic tissues, such as liver and kidney tubules and glomeruli, as well as on the surface of immune cells like macrophages, monocytes, neutrophils, basophils, and large lymphocytes. CD68 presence on these immune cells serves as a marker for macrophage activation and is involved in the phagocytosis of pathogens and cellular debris, thereby contributing to the body′s defense mechanisms. Additionally, lysosomal glycoproteins like CD68 are essential components of lysosomal membranes, providing structural integrity and protection against degradation by hydrolases, which is vital for maintaining cellular homeostasis and function. Anti-CD68 antibody (B-7) is an invaluable tool for researchers studying immune responses, macrophage biology, and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD68 Antibody (B-7) | sc-514937 | 200 µg/ml | $322.00 | |||
CD68 Antibody (B-7): m-IgG3 BP-HRP Bundle | sc-550524 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD68 (B-7) Neutralizing Peptide | sc-514937 P | 100 µg/0.5 ml | $69.00 |