CD6 Antibody (H-6): sc-373947
- CD6 Antibody (H-6) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 369-668 of CD6 of human origin
- recommended for detection of CD6 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD6 Antibody (H-6) for WB applications. These reagents are now offered in bundles with CD6 Antibody (H-6) (see ordering information below).
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CD6 Antibody (H-6) is a mouse monoclonal IgG2a antibody that detects CD6 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CD6 is a type I transmembrane glycoprotein that plays a crucial role in the immune system, particularly in the interactions between thymocytes and thymic epithelial cells, which are essential for T cell development and maturation. CD6 is characterized by a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain, and a 44-amino acid cytoplasmic domain. This structural composition facilitates CD6 binding to ligands, enhancing T cell activation and promoting immune responses. CD6 exhibits notable homology to CD5, and CD6 expression is not limited to T cells; CD6 is also found in certain B cell chronic lymphocytic leukemias and in the brain, indicating broader implications in both normal and pathological immune functions. Anti-CD6 antibody (H-6) is an invaluable tool for researchers studying T cell biology and the mechanisms underlying immune regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD6 Antibody (H-6) | sc-373947 | 200 µg/ml | $322.00 | |||
CD6 Antibody (H-6): m-IgGκ BP-HRP Bundle | sc-535346 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD6 Antibody (H-6): m-IgG2a BP-HRP Bundle | sc-546223 | 200 µg Ab; 10 µg BP | $361.00 |