CD45R Antibody (RA3-3A1): sc-19598
- CD45R Antibody (RA3-3A1) is a rat monoclonal IgG provided at 200 µg/ml
- recommended for detection of CD45R which is dependent upon the expression of exon A and specific carbohydrate residues of mouse origin by WB, IP, IF, IHC(P) and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also provided azide-free for modulation of B-cell responses in vitro and in vivo, sc-19598 L, 200 µg/0.1 ml
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD45R Antibody (RA3-3A1). This work is in progress.
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CD45R Antibody (RA3-3A1) is a rat monoclonal IgG antibody designed to target the CD45R protein. CD45R is a transmembrane glycoprotein ubiquitously expressed across hematopoietic cells and exists in multiple isoforms generated through alternative splicing of exons 4, 5, and 6, which modulates its extracellular domain structure. This structural diversity is crucial as it allows CD45R to perform distinct functions tailored to different immune cell types, while the conserved intracellular domain ensures consistent phosphotyrosine phosphatase activity essential for immune cell signaling. Anti-CD45R antibody (RA3-3A1) effectively recognizes CD45R in mouse species and is suitable for applications including western blotting (WB), immunoprecipitation (IP), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). CD45R plays a vital role in regulating tyrosine phosphorylation initiated by the TCR/CD3 complex, which is critical for the activation and function of Src and Syk family kinases such as Lck, Fyn, and ZAP-70. Understanding the intricate structure of CD45R is important for elucidating its role in immune responses and the behavior of hematopoietic cells. CD45R monoclonal antibody (RA3-3A1) serves as an essential tool for researchers studying immune signaling mechanisms, offering valuable insights into the modulation of immune cell activities.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD45R Antibody (RA3-3A1) | sc-19598 | 200 µg/ml | $322.00 | |||
CD45R Antibody (RA3-3A1) FITC | sc-19598 FITC | 200 µg/ml | $336.00 | |||
CD45R Antibody (RA3-3A1) L | sc-19598 L | 200 µg/0.1 ml | $322.00 | |||
CD45R Antibody (RA3-3A1) PE | sc-19598 PE | 200 µg/ml | $349.00 |