CD36 Antibody (ME542): sc-13572

CD36 Antibody (ME542) is a mouse monoclonal IgA kappa light chain antibody specifically developed to recognize CD36, also known as platelet glycoprotein 4 (GPIV), fatty acid translocase (FAT), glycoprotein IIIb (GPIIIB), scavenger receptor class B member 3 (SCARB3), and PAS IV. CD36 is a structurally complex membrane glycoprotein characterized by multiple transmembrane domains and extracellular regions that facilitate interaction with diverse ligands, including collagen, thrombospondin, anionic phospholipids, and oxidized low-density lipoproteins (LDL). This structural versatility is crucial for CD36′s role in mediating processes such as phagocytosis, lipid metabolism, and cell adhesion, which are essential for maintaining cellular homeostasis and supporting continuous production of mature spermatozoa. Located on the surface of platelets, monocytes, and umbilical vein endothelial cells, CD36′s structural domains enable function as a receptor and signaling molecule, influencing various physiological pathways and contributing to immune responses. The integrity of CD36′s structure is vital, as mutations can lead to platelet glycoprotein deficiency, impacting normal platelet function and hemostasis. CD36 monoclonal antibody (ME542) demonstrates reactivity in both mouse and rat species, and is recommended for applications such as immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). By targeting full-length CD36 of mouse origin, anti-CD36 antibody (ME542) allows researchers to investigate intricate structural features of CD36 and implications in cardiovascular diseases, metabolic disorders, and inflammatory conditions. CD36 (ME542) antibody is an indispensable reagent for both basic research and clinical investigations, providing critical insights into structural and functional dynamics of this important membrane glycoprotein.

The preferred CD36 antibody is CD36 Antibody (SMφ): sc-7309.