CD229 Antibody (HLy 9.1.25): sc-58992
- CD229 Antibody (HLy 9.1.25) is a mouse monoclonal IgG1 κ CD229 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against pre-B cell line 300.19 transfected with human CD229
- CD229 Antibody (HLy 9.1.25) is recommended for detection of CD229 cell surface antigen of human origin by WB, IP and FCM
- Anti-CD229 Antibody (HLy 9.1.25) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CD229 Antibody (HLy 9.1.25) for WB applications. These reagents are now offered in bundles with CD229 Antibody (HLy 9.1.25) (see ordering information below).
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CD229 Antibody (HLy 9.1.25) is a mouse monoclonal IgG1 kappa light chain antibody that detects CD229 protein of human origin by western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). Anti-CD229 antibody (HLy 9.1.25) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CD229, also known as T lymphocyte surface antigen Ly9 or lymphocyte antigen 9, is a type I membrane glycoprotein that plays a critical role in the adhesion processes between T lymphocytes and accessory cells through homophilic interactions. This interaction is essential for effective immune responses, as CD229 facilitates communication between immune cells, thereby influencing cytokine production and cytotoxic activity of lymphocytes and natural killer cells. CD229 is part of the CD2 subfamily within the immunoglobulin gene superfamily, which includes other important receptors such as CD2, CD48, CD58, CD84, CD244, and CD150. CD229 interacts with the SAP/SH2D1A protein, which is significant for the regulation of immune signaling pathways. CD229 expression occurs on mature B cells, T cells, thymocytes, and natural killer cells, highlighting CD229′s importance in the immune system′s functionality and response to pathogens.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CD229 Antibody (HLy 9.1.25) References:
- Gene structure of the mouse leukocyte cell surface molecule Ly9. | Tovar, V., et al. 2000. Immunogenetics. 51: 788-93. PMID: 10970093
- Isolation and characterization of cDNA clones for mouse Ly-9. | Sandrin, MS., et al. 1992. J Immunol. 149: 1636-41. PMID: 1506686
- Identification of Grb2 as a novel binding partner of the signaling lymphocytic activation molecule-associated protein binding receptor CD229. | Martín, M., et al. 2005. J Immunol. 174: 5977-86. PMID: 15879090
- CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. | Romero, X., et al. 2005. J Immunol. 174: 7033-42. PMID: 15905546
- Isolation and characterization of cDNA clones for Humly9: the human homologue of mouse Ly9. | Sandrin, MS., et al. 1996. Immunogenetics. 43: 13-9. PMID: 8537117
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD229 Antibody (HLy 9.1.25) | sc-58992 | 200 µg/ml | $322.00 | |||
CD229 Antibody (HLy 9.1.25): m-IgG Fc BP-HRP Bundle | sc-526923 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD229 Antibody (HLy 9.1.25): m-IgG1 BP-HRP Bundle | sc-532296 | 200 µg Ab; 20 µg BP | $361.00 | |||
CD229 Antibody (HLy 9.1.25) AC | sc-58992 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CD229 Antibody (HLy 9.1.25) HRP | sc-58992 HRP | 200 µg/ml | $322.00 | |||
CD229 Antibody (HLy 9.1.25) FITC | sc-58992 FITC | 200 µg/ml | $336.00 | |||
CD229 Antibody (HLy 9.1.25) PE | sc-58992 PE | 200 µg/ml | $349.00 | |||
CD229 Antibody (HLy 9.1.25) Alexa Fluor® 488 | sc-58992 AF488 | 200 µg/ml | $364.00 | |||
CD229 Antibody (HLy 9.1.25) Alexa Fluor® 546 | sc-58992 AF546 | 200 µg/ml | $364.00 | |||
CD229 Antibody (HLy 9.1.25) Alexa Fluor® 594 | sc-58992 AF594 | 200 µg/ml | $364.00 | |||
CD229 Antibody (HLy 9.1.25) Alexa Fluor® 647 | sc-58992 AF647 | 200 µg/ml | $364.00 | |||
CD229 Antibody (HLy 9.1.25) Alexa Fluor® 680 | sc-58992 AF680 | 200 µg/ml | $364.00 | |||
CD229 Antibody (HLy 9.1.25) Alexa Fluor® 790 | sc-58992 AF790 | 200 µg/ml | $364.00 |