



CD19 Antibody (HD237) is a mouse monoclonal IgG2b light chain antibody that detects CD19 in human samples through applications such as immunofluorescence (IF) and flow cytometry (FCM). CD19 is a crucial transmembrane glycoprotein that plays a significant role in B-cell development and activation. CD19 is selectively expressed on the surface of B-lymphocytes, where CD19 is integral to the activation of intracellular signaling pathways, including the Ras and phosphatidylinositol 3-kinase pathways. CD19′s importance lies in CD19′s ability to facilitate the cross-linking of immunoglobulin chains, which leads to the recruitment of Src family protein tyrosine kinases, essential for B-cell signaling. CD19′s expression is maintained throughout the various stages of B-cell maturation, culminating in the differentiation of B-cells into plasma cells. Additionally, CD19 forms functional complexes with other B-lymphocyte surface proteins, such as integrin β1, CD21, and CD81, which are vital for regulating B-cell development and ensuring a robust immune response. Anti-CD19 antibody (HD237) is an invaluable tool for researchers studying B-cell biology and related immunological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD19 Antibody (HD237) | sc-18884 | 200 µg/ml | $322.00 | |||
CD19 Antibody (HD237) FITC | sc-18884 FITC | 200 µg/ml | $336.00 | |||
CD19 Antibody (HD237) L | sc-18884 L | 200 µg/0.1 ml | $322.00 | |||
CD19 Antibody (HD237) PE | sc-18884 PE | 200 µg/ml | $349.00 |