CD165 Antibody (SN2 N6-D11): sc-58969

CD165 Antibody (SN2 N6-D11) is a mouse monoclonal IgG1 antibody that detects CD165 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CD165, also known as AD2, is a cell surface glycoprotein that plays a crucial role in the adhesion of thymocytes to thymic epithelial cells, which is essential for normal T cell development. This interaction facilitates the maturation and differentiation of T cells, ensuring a robust immune response. CD165 is predominantly expressed on a subset of peripheral lymphocytes and monocytes, with particularly high levels found on T-cell type acute lymphoblastic cells and nearly all platelets. CD165 is localized in various tissues, including the spleen, thymus, central nervous system, pancreatic islets, and Bowman′s capsule of the kidney, highlighting CD165′s importance in both immune function and tissue homeostasis. Anti-CD165 antibody (SN2 N6-D11) serves as an invaluable tool for researchers studying T cell biology and related pathologies, providing insights into the mechanisms of immune cell interactions and their implications in diseases.

The preferred CD165 antibody is CD165 Antibody (AD2): sc-53885.