CCT A Antibody (F-6): sc-376107
- CCT A Antibody (F-6) is a mouse monoclonal IgG1 κ CCT A antibody, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 38-67 at the N-terminus of CCT A of human origin
- CCT A Antibody (F-6) is recommended for detection of CCT A of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-CCT A Antibody (F-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for CCT A Antibody (F-6) for WB and IHC(P) applications. This reagent is now offered in a bundle with CCT A Antibody (F-6) (see ordering information below).
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CCT A Antibody (F-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects CCT A protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CCT A (F-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CCT A protein plays a crucial role in phosphatidylcholine biosynthesis, a key component of pulmonary surfactant, which reduces surface tension in alveoli and prevents lung collapse at birth. This function becomes especially important during late gestation, as glucocorticoids induce enzymes necessary for increased surfactant production, promoting fetal lung maturity. CCT A protein functions as the rate-controlling enzyme in phosphatidylcholine biosynthesis, with proper regulation being vital for cell survival in cultured eukaryotic cells. CCT A alpha isoform localizes in the nucleus and undergoes regulation through reversible phosphorylation and membrane association, demonstrating a dynamic role in cellular processes. CCT A gene resides on human chromosome 3q, with expression being critical for functional lung development in neonates.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CCT A Antibody (F-6) References:
- CTP:phosphocholine cytidylyltransferase: insights into regulatory mechanisms and novel functions. | Clement, JM. and Kent, C. 1999. Biochem Biophys Res Commun. 257: 643-50. PMID: 10208837
- Primary structure and expression of a human CTP:phosphocholine cytidylyltransferase. | Kalmar, GB., et al. 1994. Biochim Biophys Acta. 1219: 328-34. PMID: 7918629
- Gestational age dependence of 11 beta-hydroxysteroid dehydrogenase and its relationship to the enzymes of phosphatidylcholine synthesis in lung and liver of fetal rat. | Hundertmark, S., et al. 1994. Biochim Biophys Acta. 1210: 348-54. PMID: 8305490
- The gene for murine CTP:phosphocholine cytidylyltransferase (Ctpct) is located on mouse chromosome 16. | Rutherford, MS., et al. 1993. Genomics. 18: 698-701. PMID: 8307580
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CCT A Antibody (F-6) | sc-376107 | 200 µg/ml | $322.00 | |||
CCT A Antibody (F-6): m-IgG Fc BP-HRP Bundle | sc-526000 | 200 µg Ab; 10 µg BP | $361.00 | |||
CCT A Antibody (F-6) AC | sc-376107 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CCT A Antibody (F-6) HRP | sc-376107 HRP | 200 µg/ml | $322.00 | |||
CCT A Antibody (F-6) FITC | sc-376107 FITC | 200 µg/ml | $336.00 | |||
CCT A Antibody (F-6) PE | sc-376107 PE | 200 µg/ml | $349.00 | |||
CCT A Antibody (F-6) Alexa Fluor® 488 | sc-376107 AF488 | 200 µg/ml | $364.00 | |||
CCT A Antibody (F-6) Alexa Fluor® 546 | sc-376107 AF546 | 200 µg/ml | $364.00 | |||
CCT A Antibody (F-6) Alexa Fluor® 594 | sc-376107 AF594 | 200 µg/ml | $364.00 | |||
CCT A Antibody (F-6) Alexa Fluor® 647 | sc-376107 AF647 | 200 µg/ml | $364.00 | |||
CCT A Antibody (F-6) Alexa Fluor® 680 | sc-376107 AF680 | 200 µg/ml | $364.00 | |||
CCT A Antibody (F-6) Alexa Fluor® 790 | sc-376107 AF790 | 200 µg/ml | $364.00 | |||
CCT A (F-6) Neutralizing Peptide | sc-376107 P | 100 µg/0.5 ml | $69.00 |