CC2D1B Antibody (E-12): sc-271761
- CC2D1B Antibody (E-12) is a mouse monoclonal IgG1 κ CC2D1B antibody provided at 200 µg/ml
- raised against amino acids 521-778 mapping near the C-terminus of CC2D1B of human origin
- CC2D1B Antibody (E-12) is recommended for detection of CC2D1B of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-CC2D1B Antibody (E-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CC2D1B Antibody (E-12) for WB applications. These reagents are now offered in bundles with CC2D1B Antibody (E-12) (see ordering information below).
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CC2D1B Antibody (E-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects CC2D1B of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-CC2D1B antibody (E-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CC2D1B, consisting of 858 amino acids, plays a crucial role in cellular signaling and is involved in the regulation of various cellular processes, including cell proliferation and differentiation. Proper function of CC2D1B is essential for maintaining cellular homeostasis, and dysregulation has been implicated in several diseases, including cancer. CC2D1B is located in the cytoplasm and interacts with other signaling molecules, which underscores its importance in the intricate network of cellular communication. Understanding CC2D1B function and interactions can provide insights into disease mechanisms and potential therapeutic targets. CC2D1B maps to human chromosome 1, which is notable for its association with numerous genetic disorders and diseases, including various cancers and neurodevelopmental disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CC2D1B Antibody (E-12) References:
- Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. | Blackwood, DH., et al. 2001. Am J Hum Genet. 69: 428-33. PMID: 11443544
- New insights into the evolution of chromosome 1. | Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
- Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody. | McClintock, D., et al. 2006. Proc Natl Acad Sci U S A. 103: 2154-9. PMID: 16461887
- Cell biology: ageing nucleus gets out of shape. | Lans, H. and Hoeijmakers, JH. 2006. Nature. 440: 32-4. PMID: 16511477
- Chromosome 1 abnormalities in multiple myeloma. | Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
- Lamin A-dependent nuclear defects in human aging. | Scaffidi, P. and Misteli, T. 2006. Science. 312: 1059-63. PMID: 16645051
- Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness. | Hennah, W., et al. 2006. Schizophr Bull. 32: 409-16. PMID: 16699061
- The DNA sequence and biological annotation of human chromosome 1. | Gregory, SG., et al. 2006. Nature. 441: 315-21. PMID: 16710414
- Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1. | Watson, ML., et al. 1990. J Exp Med. 172: 263-72. PMID: 1694218
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CC2D1B Antibody (E-12) | sc-271761 | 200 µg/ml | $316.00 | |||
CC2D1B Antibody (E-12): m-IgG Fc BP-HRP Bundle | sc-527287 | 200 µg Ab; 10 µg BP | $354.00 | |||
CC2D1B Antibody (E-12): m-IgG1 BP-HRP Bundle | sc-532660 | 200 µg Ab; 20 µg BP | $354.00 | |||
CC2D1B Antibody (E-12) AC | sc-271761 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CC2D1B Antibody (E-12) HRP | sc-271761 HRP | 200 µg/ml | $316.00 | |||
CC2D1B Antibody (E-12) FITC | sc-271761 FITC | 200 µg/ml | $330.00 | |||
CC2D1B Antibody (E-12) PE | sc-271761 PE | 200 µg/ml | $343.00 | |||
CC2D1B Antibody (E-12) Alexa Fluor® 488 | sc-271761 AF488 | 200 µg/ml | $357.00 | |||
CC2D1B Antibody (E-12) Alexa Fluor® 546 | sc-271761 AF546 | 200 µg/ml | $357.00 | |||
CC2D1B Antibody (E-12) Alexa Fluor® 594 | sc-271761 AF594 | 200 µg/ml | $357.00 | |||
CC2D1B Antibody (E-12) Alexa Fluor® 647 | sc-271761 AF647 | 200 µg/ml | $357.00 | |||
CC2D1B Antibody (E-12) Alexa Fluor® 680 | sc-271761 AF680 | 200 µg/ml | $357.00 | |||
CC2D1B Antibody (E-12) Alexa Fluor® 790 | sc-271761 AF790 | 200 µg/ml | $357.00 |