caveolin-1 Antibody (4H312): sc-70516

caveolin-1 Antibody (4H312) is a mouse monoclonal IgG2b kappa light chain antibody that targets caveolin-1, also known as CAV1, a key structural protein of caveolae, small invaginations in the plasma membrane of various cell types. anti-caveolin-1 antibody (4H312) is raised against purified Glut4 vesicles from adipocytes of rat origin, allowing for the detection of caveolin-1 in mouse, rat, human, and to a lesser extent, hamster samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Caveolin-1 is predominantly located in the plasma membrane, where caveolin-1 plays a crucial role in the formation and maintenance of caveolae, which are involved in processes like endocytosis, signal transduction, and lipid regulation. The localization of caveolin-1 within caveolae is essential for the compartmentalization of signaling molecules, including G protein-coupled receptors, thereby facilitating efficient cellular communication and response to external stimuli. Additionally, caveolin-1 is implicated in the transcytosis of macromolecules across endothelial cells, the uptake of small molecules via potocytosis, and the regulation of cholesterol homeostasis, making caveolin-1 vital for maintaining cellular and vascular health. caveolin-1 monoclonal antibody (4H312) is available in both conjugated and non-conjugated forms, including options such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, providing researchers with versatile tools for diverse experimental setups. caveolin-1 (4H312) antibody supports in-depth investigations into the roles of caveolae in cellular physiology and pathology, facilitating advancements in understanding complex biological processes and disease mechanisms.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-caveolin-1 Antibody (4H312) has 26 citations in a variety of scientific publications.

Primary antibodies like Anti-caveolin-1 Antibody (4H312) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

caveolin-1 Antibody (4H312) Specifications

Alternate Product Name: caveolin-1

Product Clone Name: 4H312

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids:

Epitope Target: caveolin-1

Epitope Species: rat

Product Reactivity/Detection: caveolin-1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, FCM

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 26 citations in various scientific publications

Available Conjugates/Forms for caveolin-1 Antibody (4H312): FITC: Fluoroscein, PE: Phycoerythrin

The preferred caveolin-1 antibody is caveolin-1 Antibody (7C8): sc-53564.