casein kinase I substrate Substrate (CAS 154444-97-0)

The casein kinase I substrate is a pivotal tool in molecular research, particularly in elucidating the regulatory mechanisms of casein kinase I (CKI) signaling within cellular pathways. This substrate, typically a peptide sequence designed to mimic natural CKI substrates, serves as a target for phosphorylation by the enzyme. Upon phosphorylation by CKI, the substrate undergoes conformational changes, leading to downstream signaling events. Through its mechanism of action, the casein kinase I substrate enables researchers to investigate the activity and functional roles of CKI in various cellular processes, such as circadian rhythm regulation, cell cycle progression, and gene expression. Widely utilized in biochemistry, cell biology, and neuroscience studies, this substrate has provided valuable insights into CKI signaling and its implications in cellular physiology and pathology. Furthermore, its utilization has facilitated the identification of novel CKI substrates and regulatory mechanisms, contributing to a deeper understanding of the enzyme′s role in cellular signaling networks. Continued exploration using the casein kinase I substrate promises to uncover further insights into the functional significance of CKI in cellular processes, ultimately advancing our knowledge of its role in health and disease.