CARKD Antibody (A-1): sc-514529
- CARKD Antibody (A-1) is a mouse monoclonal IgG2b κ CARKD antibody provided at 200 µg/ml
- raised against amino acids 32-331 mapping within an internal region of CARKD of mouse origin
- CARKD Antibody (A-1) is recommended for detection of CARKD of mouse origin by WB, IP, IF and ELISA
- Anti-CARKD Antibody (A-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP is the preferred secondary detection reagent for CARKD Antibody (A-1) for WB applications. This reagent is now offered in a bundle with CARKD Antibody (A-1) (see ordering information below).
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SEE ALSO...
CARKD Antibody (A-1) is a mouse monoclonal IgG2b kappa light chain antibody that detects CARKD protein of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CARKD (A-1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CARKD protein, or carbohydrate kinase domain-containing protein, consists of 347 amino acids and is a member of the YjeF family, existing in three alternatively spliced isoforms. CARKD protein plays a critical role in carbohydrate metabolism, specifically in the phosphorylation of carbohydrates, which is essential for energy production and cellular signaling. Proper functioning of CARKD is vital, as disruptions in carbohydrate metabolism can lead to various metabolic disorders and impact overall cellular health. CARKD is encoded by a gene located on human chromosome 13q34, a region that harbors important tumor suppressor genes, including BRCA2 and RB1, which are implicated in cancer development. Understanding CARKD function and interactions within metabolic pathways can provide insights into potential therapeutic targets for diseases related to carbohydrate metabolism.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CARKD Antibody (A-1) References:
- The DNA sequence and analysis of human chromosome 13. | Dunham, A., et al. 2004. Nature. 428: 522-8. PMID: 15057823
- A new gene for Tourette's syndrome: a window into causal mechanisms? | Grados, MA. and Walkup, JT. 2006. Trends Genet. 22: 291-3. PMID: 16678301
- RB and cell cycle progression. | Giacinti, C. and Giordano, A. 2006. Oncogene. 25: 5220-7. PMID: 16936740
- Examination of the SLITRK1 gene in Caucasian patients with Tourette syndrome. | Deng, H., et al. 2006. Acta Neurol Scand. 114: 400-2. PMID: 17083340
- Non-disjunction of chromosome 13. | Bugge, M., et al. 2007. Hum Mol Genet. 16: 2004-10. PMID: 17584770
- Variable expressivity in Patau syndrome is not all related to trisomy 13 mosaicism. | Hsu, HF. and Hou, JW. 2007. Am J Med Genet A. 143A: 1739-48. PMID: 17603803
- The origin of trisomy 13. | Hall, HE., et al. 2007. Am J Med Genet A. 143A: 2242-8. PMID: 17853475
- Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture. | Hassler, M., et al. 2007. Mol Cell. 28: 371-85. PMID: 17996702
- BRCA2: a universal recombinase regulator. | Thorslund, T. and West, SC. 2007. Oncogene. 26: 7720-30. PMID: 18066084
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CARKD Antibody (A-1) | sc-514529 | 200 µg/ml | $316.00 | |||
CARKD Antibody (A-1): m-IgG2b BP-HRP Bundle | sc-548799 | 200 µg Ab; 10 µg BP | $354.00 | |||
CARKD Antibody (A-1) AC | sc-514529 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CARKD Antibody (A-1) HRP | sc-514529 HRP | 200 µg/ml | $316.00 | |||
CARKD Antibody (A-1) FITC | sc-514529 FITC | 200 µg/ml | $330.00 | |||
CARKD Antibody (A-1) PE | sc-514529 PE | 200 µg/ml | $343.00 | |||
CARKD Antibody (A-1) Alexa Fluor® 488 | sc-514529 AF488 | 200 µg/ml | $357.00 | |||
CARKD Antibody (A-1) Alexa Fluor® 546 | sc-514529 AF546 | 200 µg/ml | $357.00 | |||
CARKD Antibody (A-1) Alexa Fluor® 594 | sc-514529 AF594 | 200 µg/ml | $357.00 | |||
CARKD Antibody (A-1) Alexa Fluor® 647 | sc-514529 AF647 | 200 µg/ml | $357.00 | |||
CARKD Antibody (A-1) Alexa Fluor® 680 | sc-514529 AF680 | 200 µg/ml | $357.00 | |||
CARKD Antibody (A-1) Alexa Fluor® 790 | sc-514529 AF790 | 200 µg/ml | $357.00 |