Calcitriol Antibody (ID1-25A) is a mouse monoclonal IgG antibody that detects Calcitriol in non-species reactive samples by enzyme-linked immunosorbent assay (ELISA). Calcitriol, also known as 1,25(OH)2 Vitamin D3, is the active form of vitamin D and plays a crucial role in maintaining calcium and phosphate homeostasis in the body. Calcitriol is synthesized in the kidneys from its precursor, Calcidiol, through the action of the enzyme 1α-OHase. Calcitriol binds to the vitamin D receptor (VDR), which subsequently regulates the transcription of various target genes involved in calcium and phosphate metabolism. This regulation is vital for several physiological processes, including the absorption of calcium and phosphate in the intestines, the resorption of these minerals from bones, and their reabsorption in the kidneys, all of which contribute to the proper mineralization of bone. Calcitriol has been shown to play a role in inhibiting cellular proliferation, promoting cellular differentiation, and modulating immune responses, highlighting its significance beyond mineral metabolism. Anti-Calcitriol antibody (ID1-25A) serves as an essential tool for researchers studying the multifaceted roles of this important steroid hormone in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Calcitriol Antibody (ID1-25A) | sc-73498 | 100 µg/ml | $322.00 |