C6 Antibody (3G11): sc-66191
- C6 Antibody (3G11) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against purified C6 of rat origin
- recommended for detection of C6 of mouse and rat origin by WB
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for C6 Antibody (3G11) for WB applications. These reagents are now offered in bundles with C6 Antibody (3G11) (see ordering information below).
C6 Antibody (3G11) is a mouse monoclonal IgG1 antibody that detects C6 in mouse and rat samples through western blotting (WB). C6 is a crucial component of the complement cascade, a multi-protein system integral to the innate immune response, which functions to eliminate pathogens from an infected host. This 934 amino acid secreted protein is essential for the formation of the membrane attack complex, which is responsible for lysing target cells. C6 is expressed in two transcript variants and features a complex structure that includes one EGF-like domain, one LDL-receptor class A domain, one MACPF domain, two Sushi domains, and three TSP type-1 domains, all of which contribute to its functional role in immune defense. The presence of C6 is vital, as deficiencies in this protein have been linked to an increased susceptibility to bacterial infections, underscoring its importance in maintaining a robust innate immune system. Anti-C6 antibody (3G11) is an invaluable tool for researchers studying the complement system and its implications in immune responses.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
C6 Antibody (3G11) | sc-66191 | 200 µg/ml | $316.00 | |||
C6 Antibody (3G11): m-IgG Fc BP-HRP Bundle | sc-539210 | 200 µg Ab; 10 µg BP | $354.00 | |||
C6 Antibody (3G11): m-IgG1 BP-HRP Bundle | sc-541328 | 200 µg Ab; 20 µg BP | $354.00 |