C12orf50 Antibody (E-1): sc-377275

C12orf50 Antibody (E-1) is a mouse monoclonal IgM antibody that detects C12orf50 of human, mouse, and rat origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-C12orf50 antibody (E-1) is available as a non-conjugated format. C12orf50, located on chromosome 12, shows potential involvement in various skeletal deformities and developmental disorders. C12orf50 plays a role in critical cellular processes, though specific functions remain under investigation. C12orf50 may interact with proteins involved in signaling pathways that regulate cell growth and differentiation, essential for normal skeletal development and function. Research into C12orf50 interactions and pathways could reveal mechanisms underlying skeletal deformities linked to chromosome 12, including hypochondrogenesis and achondrogenesis. Anti-C12orf50 antibody (E-1)′s multi-species detection capability makes this reagent valuable for studying C12orf50′s role in health and disease, particularly in developmental biology and genetic disorders.

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C12orf50 Antibody (E-1) References:

1. The genomic context of natural killer receptor extended gene families.  |  Trowsdale, J., et al. 2001. Immunol Rev. 181: 20-38. PMID: 11513141
2. Genotype/phenotype analysis in a patient with pure and complete trisomy 12p.  |  Zumkeller, W., et al. 2004. Am J Med Genet A. 129A: 261-4. PMID: 15326625
3. The phenotypic spectrum of COL2A1 mutations.  |  Nishimura, G., et al. 2005. Hum Mutat. 26: 36-43. PMID: 15895462
4. Comparative genomics of natural killer cell receptor gene clusters.  |  Kelley, J., et al. 2005. PLoS Genet. 1: 129-39. PMID: 16132082
5. The natural history of trisomy 12p.  |  Segel, R., et al. 2006. Am J Med Genet A. 140: 695-703. PMID: 16502429
6. Noonan syndrome.  |  van der Burgt, I. 2007. Orphanet J Rare Dis. 2: 4. PMID: 17222357
7. Cytogenetic and molecular analysis in trisomy 12p.  |  Allen, TL., et al. 1996. Am J Med Genet. 63: 250-6. PMID: 8723118
8. Low basal transcripts of the COL2A1 collagen gene from lymphoblasts show alternative splicing of exon 12 in the Kniest form of spondyloepiphyseal dysplasia.  |  Yang, W. and Cole, WG. 1998. Hum Mutat. Suppl 1: S1-2. PMID: 9452022

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-C12orf50 Antibody (E-1) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-C12orf50 Antibody (E-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

C12orf50 Antibody (E-1) Specifications

Alternate Product Name: C12orf50

Product Clone Name: E-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 283-315

Epitope Target: C12orf50

Epitope Species: human

Product Reactivity/Detection: C12orf50 of human origin, 1700017N19Rik of mouse origin and the corresponding rat homolog

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for C12orf50 Antibody (E-1): P: Blocking Peptide