c-Jun Antibody (B-2): sc-376488

c-Jun Antibody (B-2) is a mouse monoclonal IgG3 kappa light chain antibody that detects c-Jun protein of mouse, rat, human, and chicken origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-c-Jun antibody (B-2) is available in a non-conjugated form, providing flexibility for various experimental needs. c-Jun plays a crucial role in cellular processes as a key component of the transcription factor AP-1, which is essential for regulating gene expression in response to various stimuli, including growth factors and stress signals. c-Jun′s ability to form both homo- and heterodimers with other members of the Jun and Fos families allows binding to the TPA-response element (TRE) with high affinity, particularly when paired with Fos proteins. c-Jun interaction with Ha-Ras enhances transcriptional activity, highlighting importance in oncogenic signaling pathways. Post-translational modifications, such as phosphorylation, can modulate c-Jun activity and stability. Understanding c-Jun dynamics and interactions is vital for elucidating mechanisms underlying cellular responses to external stimuli and disease development, including cancer.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-c-Jun Antibody (B-2) has 9 citations in a variety of scientific publications.

Primary antibodies like Anti-c-Jun Antibody (B-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

c-Jun Antibody (B-2) Specifications

Alternate Product Name: c-Jun

Product Clone Name: B-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 237-273

Epitope Target: c-Jun

Epitope Species: mouse

Product Reactivity/Detection: c-Jun, Jun B and Jun D p39

Species Reactivity/Detection: mouse, rat, human, chicken

Additional Mammalian Reactivity: canine, bovine, porcine and avian

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 9 citations in various scientific publications

Available Conjugates/Forms for c-Jun Antibody (B-2): P: Blocking Peptide, X: TransCruz Reagent

The preferred p-c-Jun antibody is p-c-Jun Antibody (KM-1): sc-822.