c-IAP2 Antibody (Ac-71) is a mouse monoclonal IgG1 kappa light chain antibody that detects c-IAP2 protein of human origin by western blotting (WB). anti-c-IAP2 antibody (Ac-71) is available as a non-conjugated format, providing a reliable tool for researchers studying apoptosis regulation. c-IAP2 protein, also known as BIRC3, plays a crucial role in inhibiting programmed cell death, which is vital for maintaining cellular homeostasis and preventing excessive cell loss in various physiological processes. c-IAP2 is primarily located in the cytoplasm and is involved in regulating apoptosis through interaction with key signaling pathways. Notably, c-IAP2 can bind to tumor necrosis factor receptor-associated factors (TRAFs), which are essential for mediating the effects of tumor necrosis factor (TNF) signaling. By modulating these interactions, c-IAP2 helps prevent TNF-induced apoptosis, thereby influencing immune responses and cell survival. Understanding c-IAP2 function and localization is important for elucidating its role in cancer biology and therapeutic resistance, making c-IAP2 (Ac-71) monoclonal antibody an invaluable resource for researchers investigating these critical pathways.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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c-IAP2 Antibody (Ac-71) References:
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