c-Fms/CSF-1R Antibody (5J15): sc-70452
- c-Fms/CSF-1R Antibody (5J15) is a rat monoclonal IgG1 provided at 200 µg/ml
- recommended for detection of c-Fms gp130 and gp150 of mouse, rat and human origin by WB and IP
- See c-Fms/CSF-1R (B-8): sc-46662 for c-Fms/CSF-1R antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for c-Fms/CSF-1R Antibody (5J15). This work is in progress.
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c-Fms/CSF-1R Antibody (5J15) is a rat monoclonal IgG1 antibody that detects c-Fms/CSF-1R in mouse, rat, and human samples through western blotting (WB) and immunoprecipitation (IP) applications. c-Fms/CSF-1R, also known as macrophage colony-stimulating factor receptor (M-CSFR), FIM2, or CD115, is a transmembrane tyrosine kinase receptor that plays a crucial role in the growth and differentiation of myeloid cells. This receptor is encoded by the c-Fms proto-oncogene and is predominantly expressed in mononuclear phagocytes, oocytes, decidual cells, trophoblastic cells, and certain myoblasts. The significance of c-Fms/CSF-1R lies in its ability to mediate the functions of macrophage colony-stimulating factor (M-CSF), a glycoprotein essential for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF is also a key player in the inflammatory response, regulating the release of proinflammatory cytokines from macrophages, which underscores its importance in both immune response and tissue homeostasis. Anti-c-Fms/CSF-1R antibody (5J15) is an invaluable tool for researchers studying myeloid cell biology and the mechanisms underlying inflammation and immune regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
c-Fms/CSF-1R Antibody (5J15) | sc-70452 | 200 µg/ml | $322.00 |