Date published: 2026-5-13

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c-Fms/CSF-1R Activators

c-Fms/CSF-1R Activators constitute a specific group of chemical compounds known for their capacity to modulate the activity of the colony-stimulating factor 1 receptor (CSF-1R), also referred to as c-Fms. This chemical class functions by interacting with and enhancing the signaling pathways associated with c-Fms/CSF-1R, a transmembrane receptor tyrosine kinase that plays a pivotal role in mediating cellular responses to colony-stimulating factor 1 (CSF-1). c-Fms/CSF-1R is recognized for its involvement in various biological processes, including cell proliferation, differentiation, and immune regulation.

c-Fms/CSF-1R Activators exert their influence through specific molecular interactions that may amplify the downstream effects of c-Fms/CSF-1R-mediated signaling, contributing to the fine-tuning of cell growth, immune cell development, and tissue homeostasis. The intricate mechanisms through which c-Fms/CSF-1R Activators impact c-Fms/CSF-1R-related pathways remain a subject of ongoing scientific investigation, offering insights into the complex interplay between growth factor signaling, cellular responses to extracellular cues, and developmental processes. The specific ways in which this chemical class engages with c-Fms/CSF-1R underscore its significance in unraveling the intricacies of cell communication and enhancing our understanding across various scientific domains.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

GM-CSF

83869-56-1sc-280759
5 µg
$516.00
1
(0)

GM-CSF is another cytokine that can activate the CSF-1R receptor. While it primarily stimulates the production of granulocytes and macrophages, GM-CSF can also affect other immune cell types and play a role in inflammation.

Angiotensin II, Human

4474-91-3sc-363643
sc-363643A
sc-363643B
sc-363643C
1 mg
5 mg
25 mg
100 mg
$51.00
$100.00
$310.00
$690.00
3
(1)

Angiotensin II, a hormone involved in regulating blood pressure, can activate CSF-1R in certain contexts. It has been implicated in promoting vascular inflammation and tissue remodeling through CSF-1R signaling.

PGD2 (Prostaglandin D2)

41598-07-6sc-201221
sc-201221A
1 mg
10 mg
$96.00
$583.00
4
(1)

Prostaglandins, lipid compounds with diverse physiological functions, can activate CSF-1R signaling in macrophages. They are involved in inflammation and immune responses.