Bystin Antibody (clone 19): sc-80001
- Bystin Antibody (clone 19) is a mouse monoclonal IgM κ, cited in 2 publications, provided at 200 µg/ml
- raised against a peptide corresponding to amino acids 215-223 of Bystin of human origin
- recommended for detection of Bystin of human origin by WB, IF and IHC(P)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Bystin Antibody (clone 19). This work is in progress.
QUICK LINKS
SEE ALSO...
Bystin Antibody (clone 19) is a mouse monoclonal IgM antibody that detects Bystin in human samples through applications such as western blotting (WB), immunofluorescence (IF), and immunohistochemistry. Bystin is an evolutionarily conserved protein that plays a crucial role in ribosome biogenesis, as Bystin associates with the 40S ribosomal subunit in the nucleus and interacts with proteins like Trophinin and Tastin in the cytoplasm, facilitating cell adhesion. Bystin′s localization to both the nucleolus and cytoplasm underscores Bystin′s dual role in cellular processes, including RNA processing and cell proliferation. Notably, Bystin knockdown not only inhibits cell proliferation but also disrupts the processing of the 18S component of the ribosomal subunit, indicating Bystin′s essential function in ribosome formation. Furthermore, Bystin expression is critical for progression beyond the 16-cell stage in preimplantation embryos. Additionally, Bystin is overexpressed in various human cancers, highlighting Bystin′s potential involvement in tumorigenesis and cell growth regulation. Anti-Bystin antibody (clone 19) is an invaluable tool for researchers investigating the multifaceted roles of Bystin in cellular biology and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bystin Antibody (clone 19) | sc-80001 | 200 µg/ml | $322.00 |