Brucella abortus LPS Antibody (3531): sc-58096

Brucella abortus LPS Antibody (3531) is a mouse monoclonal IgG2a antibody that detects Brucella abortus in Brucella abortus by western blotting (WB). Brucella abortus is a significant pathogen known for causing bovine brucellosis, which can lead to severe reproductive issues in cattle, including spontaneous abortion and infertility. This bacterium primarily infects the placenta and fetus of pregnant cows, posing a serious threat to livestock health and agricultural productivity. Notably, Brucella abortus employs cyclic β-1,2-glucan as a virulence factor, which plays a crucial role in adapting to hypo-osmotic environments, thereby enhancing survival within the host. Additionally, to combat iron deprivation—a common challenge in both natural and host environments—Brucella abortus secretes specific siderophores, including 2,3-dihydroxybenzoic acid and brucebactin, which are regulated by IRR. This regulation is vital for pathogenicity, as iron availability ensures essential metabolic processes, ultimately influencing infection severity. Brucella abortus LPS (3531) monoclonal antibody serves as an essential tool for researchers studying Brucella infection mechanisms and host immune response, providing valuable insights into potential therapeutic targets and strategies for disease control.

The preferred Brucella abortus LPS antibody is Brucella abortus LPS Antibody (3535): sc-58097.