Brucella abortus LPS Antibody (3535): sc-58097

Brucella abortus LPS Antibody (3535) is a mouse monoclonal IgG1 antibody that detects Brucella abortus LPS protein of Brucella abortus origin by western blotting (WB). Anti-Brucella abortus LPS antibody (3535) is available as a non-conjugated format. Brucella abortus is a small, Gram-negative coccobacillus and is the causative agent of bovine brucellosis, a significant infectious disease that can lead to spontaneous abortion, premature calving, and infertility in cattle. The importance of Brucella abortus lies not only in its impact on livestock health but also in its potential to infect humans, primarily through the consumption of unpasteurized milk or contact with infected animals. The LPS of Brucella abortus plays a crucial role in virulence, as LPS helps the bacterium evade the host′s immune response and establish infection. Additionally, Brucella abortus employs cyclic β-1,2-glucan as a virulence factor to manage hypo-osmotic stress, which is vital for survival in various environments. To address iron deprivation, a common challenge for Brucella abortus in both natural and host settings, the bacterium secretes siderophores such as 2,3-dihydroxybenzoic acid and brucebactin, regulated by IRR protein. The ability of Brucella abortus to adapt and thrive in hostile conditions underscores the importance of studying LPS and related proteins, making Brucella abortus LPS (3535) monoclonal antibody an essential tool for researchers investigating this pathogen.

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Brucella abortus LPS Antibody (3535) References:

1. Brucella abortus rough mutants induce macrophage oncosis that requires bacterial protein synthesis and direct interaction with the macrophage.  |  Pei, J., et al. 2006. Infect Immun. 74: 2667-75. PMID: 16622203
2. Vaccination with live Escherichia coli expressing Brucella abortus Cu/Zn superoxide-dismutase: II. Induction of specific CD8+ cytotoxic lymphocytes and sensitized CD4+ IFN-gamma-producing cell.  |  Andrews, E., et al. 2006. Microbiol Immunol. 50: 389-93. PMID: 16714846
3. Proteomic analysis of Brucella abortus cell envelope and identification of immunogenic candidate proteins for vaccine development.  |  Connolly, JP., et al. 2006. Proteomics. 6: 3767-80. PMID: 16739129
4. Deletion of znuA virulence factor attenuates Brucella abortus and confers protection against wild-type challenge.  |  Yang, X., et al. 2006. Infect Immun. 74: 3874-9. PMID: 16790759
5. Evaluation of protection afforded by Brucella abortus and Brucella melitensis unmarked deletion mutants exhibiting different rates of clearance in BALB/c mice.  |  Kahl-McDonagh, MM. and Ficht, TA. 2006. Infect Immun. 74: 4048-57. PMID: 16790778
6. The Brucella abortus cyclic beta-1,2-glucan virulence factor is substituted with O-ester-linked succinyl residues.  |  Roset, MS., et al. 2006. J Bacteriol. 188: 5003-13. PMID: 16816173
7. RecA and RadA proteins of Brucella abortus do not perform overlapping protective DNA repair functions following oxidative burst.  |  Roux, CM., et al. 2006. J Bacteriol. 188: 5187-95. PMID: 16816190
8. Irr regulates brucebactin and 2,3-dihydroxybenzoic acid biosynthesis, and is implicated in the oxidative stress resistance and intracellular survival of Brucella abortus.  |  Martínez, M., et al. 2006. Microbiology (Reading). 152: 2591-2598. PMID: 16946254
9. Abortion due to Brucella abortus in sheep in Nigeria.  |  Ocholi, RA., et al. 2005. Rev Sci Tech. 24: 973-9. PMID: 16642768

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Brucella abortus LPS Antibody (3535) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Brucella abortus LPS Antibody (3535) Specifications

Alternate Product Name: Brucella abortus LPS

Product Clone Name: 3535

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Brucella abortus LPS

Epitope Species: Brucella abortus

Product Reactivity/Detection: Brucella abortus

Species Reactivity/Detection: Brucella abortus

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Brucella abortus LPS Antibody (3535): N/A