Brn-3a/BRN3A/POU4F1 Antibody (H-6): sc-390078
- Brn-3a/BRN3A/POU4F1 Antibody (H-6) is a mouse monoclonal IgG1 κ, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 97-135 near the N-terminus of Brn-3a of human origin
- recommended for detection of Brn-3a of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-390078 X, 200 µg/0.1 ml)
- See Brn-3a/BRN3A/POU4F1 (14A6): sc-8429 for Brn-3a/BRN3A/POU4F1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Brn-3a/BRN3A/POU4F1 Antibody (H-6) for WB applications. These reagents are now offered in bundles with Brn-3a/BRN3A/POU4F1 Antibody (H-6) (see ordering information below).
Brn-3a Antibody (H-6) is a mouse monoclonal IgG1 antibody that detects Brn-3a in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Brn-3a is a member of the Brn family of transcription factors, which play a pivotal role in the early embryonic development of the central nervous system by regulating gene expression in a highly restricted subset of neurons. Notably, Brn-3a contains two functional transactivating domains located at both the amino-terminus and carboxy-terminus, which are essential for stimulating transcription effectively. This structural feature is crucial as Brn-3a activates target genes necessary for neuronal differentiation and survival, thereby influencing the development of neural circuits. Additionally, Brn-3a′s interaction with other proteins, such as Brn-3b, which acts as a transcriptional repressor, highlights the complex regulatory networks that govern neuronal development. Anti-Brn-3a antibody (H-6) is an invaluable tool for researchers studying the mechanisms of transcriptional regulation in neurodevelopment and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Brn-3a/BRN3A/POU4F1 Antibody (H-6) | sc-390078 | 200 µg/ml | $322.00 | |||
Brn-3a/BRN3A/POU4F1 Antibody (H-6): m-IgG Fc BP-HRP Bundle | sc-540752 | 200 µg Ab; 10 µg BP | $361.00 | |||
Brn-3a/BRN3A/POU4F1 Antibody (H-6): m-IgG1 BP-HRP Bundle | sc-542348 | 200 µg Ab; 20 µg BP | $361.00 | |||
Brn-3a/BRN3A/POU4F1 (H-6) Neutralizing Peptide | sc-390078 P | 100 µg/0.5 ml | $69.00 | |||
Brn-3a/BRN3A/POU4F1 Antibody (H-6) X | sc-390078 X | 200 µg/0.1 ml | $322.00 |