Brn-2/BRN2/POU3F2 Antibody (C-2): sc-393334
- Brn-2/BRN2/POU3F2 Antibody (C-2) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 404-443 at the C-terminus of Brn-2 of human origin
- recommended for detection of Brn-2 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-393334 X, 200 µg/0.1 ml)
- See Brn-2/BRN2/POU3F2 (B-2): sc-393324 for Brn-2/BRN2/POU3F2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Brn-2/BRN2/POU3F2 Antibody (C-2) for WB applications. This reagent is now offered in a bundle with Brn-2/BRN2/POU3F2 Antibody (C-2) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Brn-2 Antibody (C-2) is a mouse monoclonal IgG2b antibody that detects Brn-2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Brn-2 is a member of the Brn family of transcription factors, specifically classified as a class III POU domain protein, and plays a pivotal role in the early embryonic development of the central nervous system. Brn-2 is predominantly expressed during the development of the forebrain and is coexpressed in most layer II-V cortical neurons, where Brn-2 is essential for regulating the initiation of radial migration of cortical neurons. This process is crucial for proper brain architecture and function, as Brn-2 ensures that neurons migrate to their appropriate locations during development. Additionally, Brn-2 is implicated in the differentiation of smooth muscle cells, highlighting Brn-2′s importance beyond neuronal development. Brn-2′s structure includes two functional transactivating domains, which facilitate Brn-2′s role in gene regulation, and Brn-2′s interactions with other proteins in the Brn family, such as Brn-3a and Brn-3b, further underscore Brn-2′s significance in transcriptional control. anti-Brn-2 antibody (C-2) is an invaluable tool for researchers studying neuronal development and the molecular mechanisms underlying various neurological conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Brn-2/BRN2/POU3F2 Antibody (C-2) | sc-393334 | 200 µg/ml | $322.00 | |||
Brn-2/BRN2/POU3F2 Antibody (C-2): m-IgGκ BP-HRP Bundle | sc-535755 | 200 µg Ab; 40 µg BP | $361.00 | |||
Brn-2/BRN2/POU3F2 (C-2) Neutralizing Peptide | sc-393334 P | 100 µg/0.5 ml | $69.00 | |||
Brn-2/BRN2/POU3F2 Antibody (C-2) X | sc-393334 X | 200 µg/0.1 ml | $322.00 |